Smyth P - Search Results

1

DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models.

Johnston MC, Nicoll JA, Redmond KM, Smyth P, Greene MK, McDaid WJ, Chan DKW, Crawford N, Stott KJ, Fox JP, Straubinger NL, Roche S, Clynes M, Straubinger RM, Longley DB, Scott CJ. Johnston MC, et al. Among authors: smyth p. J Control Release. 2020 Aug 10;324:610-619. doi: 10.1016/j.jconrel.2020.05.046. Epub 2020 Jun 3. J Control Release. 2020. PMID: 32504778 Free PMC article.

2

Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles.

Jiang L, Greene MK, Insua JL, Pessoa JS, Small DM, Smyth P, McCann AP, Cogo F, Bengoechea JA, Taggart CC, Scott CJ. Jiang L, et al. Among authors: smyth p. J Control Release. 2018 Jun 10;279:316-325. doi: 10.1016/j.jconrel.2018.04.040. Epub 2018 Apr 25. J Control Release. 2018. PMID: 29704616

3

Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours.

McDaid WJ, Greene MK, Johnston MC, Pollheimer E, Smyth P, McLaughlin K, Van Schaeybroeck S, Straubinger RM, Longley DB, Scott CJ. McDaid WJ, et al. Among authors: smyth p. Nanoscale. 2019 Nov 14;11(42):20261-20273. doi: 10.1039/c9nr07257h. Epub 2019 Oct 18. Nanoscale. 2019. PMID: 31626255 Free PMC article.

4

FLIP(L): the pseudo-caspase.

Smyth P, Sessler T, Scott CJ, Longley DB. Smyth P, et al. FEBS J. 2020 Oct;287(19):4246-4260. doi: 10.1111/febs.15260. Epub 2020 Mar 12. FEBS J. 2020. PMID: 32096279 Free PMC article. Review.

5

Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors.

McDaid WJ, Lissin N, Pollheimer E, Greene M, Leach A, Smyth P, Bossi G, Longley D, Cole DK, Scott CJ. McDaid WJ, et al. Among authors: smyth p. Nanoscale. 2021 Sep 17;13(35):15010-15020. doi: 10.1039/d1nr04001d. Nanoscale. 2021. PMID: 34533174 Free PMC article.

6

Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe.

Cogo F , Poreba M , Rut W , Groborz K , Smyth P , Johnston MC , Williams R , Longley DB , Burden RE , Salvesen GS , Drag M , Scott CJ . Cogo F , et al. Among authors: smyth p. Nanoscale. 2019 Jan 3;11(2):742-751. doi: 10.1039/c8nr07859a. Nanoscale. 2019. PMID: 30566168 Free PMC article.

7

Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature.

Leach A , Smyth P , Ferguson L , Steven J , Greene MK , Branco CM , McCann AP , Porter A , Barelle CJ , Scott CJ . Leach A , et al. Among authors: smyth p. Nanoscale. 2020 Jul 21;12(27):14751-14763. doi: 10.1039/d0nr02962a. Epub 2020 Jul 6. Nanoscale. 2020. PMID: 32626858

8

USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells.

McCann AP, Smyth P, Cogo F, McDaid WJ, Jiang L, Lin J, Evergren E, Burden RE, Van Schaeybroeck S, Scott CJ, Burrows JF. McCann AP, et al. Among authors: smyth p. Cell Commun Signal. 2018 Nov 8;16(1):77. doi: 10.1186/s12964-018-0291-5. Cell Commun Signal. 2018. PMID: 30409180 Free PMC article.

9

Development of next generation nanomedicine-based approaches for the treatment of cancer: we've barely scratched the surface.

Tracey SR, Smyth P, Barelle CJ, Scott CJ. Tracey SR, et al. Among authors: smyth p. Biochem Soc Trans. 2021 Nov 1;49(5):2253-2269. doi: 10.1042/BST20210343. Biochem Soc Trans. 2021. PMID: 34709394 Free PMC article. Review.

10

Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.

Spence S, Greene MK, Fay F, Hams E, Saunders SP, Hamid U, Fitzgerald M, Beck J, Bains BK, Smyth P, Themistou E, Small DM, Schmid D, O'Kane CM, Fitzgerald DC, Abdelghany SM, Johnston JA, Fallon PG, Burrows JF, McAuley DF, Kissenpfennig A, Scott CJ. Spence S, et al. Among authors: smyth p. Sci Transl Med. 2015 Sep 2;7(303):303ra140. doi: 10.1126/scitranslmed.aab3459. Sci Transl Med. 2015. PMID: 26333936

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