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A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.
Wada Y, Nithichanon A, Nobusawa E, Moise L, Martin WD, Yamamoto N, Terahara K, Hagiwara H, Odagiri T, Tashiro M, Lertmemongkolchai G, Takeyama H, De Groot AS, Ato M, Takahashi Y. Wada Y, et al. Among authors: takeyama h. Sci Rep. 2017 Apr 28;7(1):1283. doi: 10.1038/s41598-017-01372-5. Sci Rep. 2017. PMID: 28455520 Free PMC article.
IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody.
Saito S, Sano K, Suzuki T, Ainai A, Taga Y, Ueno T, Tabata K, Saito K, Wada Y, Ohara Y, Takeyama H, Odagiri T, Kageyama T, Ogawa-Goto K, Multihartina P, Setiawaty V, Pangesti KNA, Hasegawa H. Saito S, et al. Among authors: takeyama h. PLoS Pathog. 2019 Jan 3;15(1):e1007427. doi: 10.1371/journal.ppat.1007427. eCollection 2019 Jan. PLoS Pathog. 2019. PMID: 30605488 Free PMC article.
Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice.
Matsumura T, Ikebe T, Arikawa K, Hosokawa M, Aiko M, Iguchi A, Togashi I, Kai S, Ohara S, Ohara N, Ohnishi M, Watanabe H, Kobayashi K, Takeyama H, Yamasaki S, Takahashi Y, Ato M. Matsumura T, et al. Among authors: takeyama h. Cell Rep. 2019 Apr 9;27(2):561-571.e6. doi: 10.1016/j.celrep.2019.03.056. Cell Rep. 2019. PMID: 30970258 Free article.
Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies.
Adachi Y, Tonouchi K, Nithichanon A, Kuraoka M, Watanabe A, Shinnakasu R, Asanuma H, Ainai A, Ohmi Y, Yamamoto T, Ishii KJ, Hasegawa H, Takeyama H, Lertmemongkolchai G, Kurosaki T, Ato M, Kelsoe G, Takahashi Y. Adachi Y, et al. Among authors: takeyama h. Nat Commun. 2019 Aug 28;10(1):3883. doi: 10.1038/s41467-019-11821-6. Nat Commun. 2019. PMID: 31462639 Free PMC article.
777 results