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Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach.
Wright MH, Clough B, Rackham MD, Rangachari K, Brannigan JA, Grainger M, Moss DK, Bottrill AR, Heal WP, Broncel M, Serwa RA, Brady D, Mann DJ, Leatherbarrow RJ, Tewari R, Wilkinson AJ, Holder AA, Tate EW. Wright MH, et al. Among authors: bottrill ar. Nat Chem. 2014 Feb;6(2):112-21. doi: 10.1038/nchem.1830. Epub 2013 Dec 22. Nat Chem. 2014. PMID: 24451586 Free PMC article.
Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.
Saini E, Zeeshan M, Brady D, Pandey R, Kaiser G, Koreny L, Kumar P, Thakur V, Tatiya S, Katris NJ, Limenitakis RS, Kaur I, Green JL, Bottrill AR, Guttery DS, Waller RF, Heussler V, Holder AA, Mohmmed A, Malhotra P, Tewari R. Saini E, et al. Among authors: bottrill ar. Sci Rep. 2017 Nov 14;7(1):15577. doi: 10.1038/s41598-017-15781-z. Sci Rep. 2017. PMID: 29138437 Free PMC article.
Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission.
Pandey R, Abel S, Boucher M, Wall RJ, Zeeshan M, Rea E, Freville A, Lu XM, Brady D, Daniel E, Stanway RR, Wheatley S, Batugedara G, Hollin T, Bottrill AR, Gupta D, Holder AA, Le Roch KG, Tewari R. Pandey R, et al. Among authors: bottrill ar. Cell Rep. 2020 Feb 11;30(6):1883-1897.e6. doi: 10.1016/j.celrep.2020.01.033. Cell Rep. 2020. PMID: 32049018 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34005212
Plasmodium ARK2 and EB1 drive unconventional spindle dynamics, during chromosome segregation in sexual transmission stages.
Zeeshan M, Rea E, Abel S, Vukušić K, Markus R, Brady D, Eze A, Rashpa R, Balestra AC, Bottrill AR, Brochet M, Guttery DS, Tolić IM, Holder AA, Le Roch KG, Tromer EC, Tewari R. Zeeshan M, et al. Among authors: bottrill ar. Nat Commun. 2023 Sep 13;14(1):5652. doi: 10.1038/s41467-023-41395-3. Nat Commun. 2023. PMID: 37704606 Free PMC article.
73 results