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REV7 is required for processing AID initiated DNA lesions in activated B cells.
Yang D, Sun Y, Chen J, Zhang Y, Fan S, Huang M, Xie X, Cai Y, Shang Y, Gui T, Sun L, Hu J, Dong J, Yeap LS, Wang X, Xiao W, Meng FL. Yang D, et al. Among authors: cai y. Nat Commun. 2020 Jun 4;11(1):2812. doi: 10.1038/s41467-020-16632-8. Nat Commun. 2020. PMID: 32499490 Free PMC article.
DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
Hao Q, Zhan C, Lian C, Luo S, Cao W, Wang B, Xie X, Ye X, Gui T, Voena C, Pighi C, Wang Y, Tian Y, Wang X, Dai P, Cai Y, Liu X, Ouyang S, Sun S, Hu Q, Liu J, Ye Y, Zhao J, Lu A, Wang JY, Huang C, Su B, Meng FL, Chiarle R, Pan-Hammarström Q, Yeap LS. Hao Q, et al. Among authors: cai y. Sci Immunol. 2023 Mar 31;8(81):eade1167. doi: 10.1126/sciimmunol.ade1167. Epub 2023 Mar 24. Sci Immunol. 2023. PMID: 36961908 Free PMC article.
Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation.
Wang Y, Zhang S, Yang X, Hwang JK, Zhan C, Lian C, Wang C, Gui T, Wang B, Xie X, Dai P, Zhang L, Tian Y, Zhang H, Han C, Cai Y, Hao Q, Ye X, Liu X, Liu J, Cao Z, Huang S, Song J, Pan-Hammarström Q, Zhao Y, Alt FW, Zheng X, Da LT, Yeap LS, Meng FL. Wang Y, et al. Among authors: cai y. Cell. 2023 May 11;186(10):2193-2207.e19. doi: 10.1016/j.cell.2023.03.030. Epub 2023 Apr 24. Cell. 2023. PMID: 37098343 Free article.
C-to-G editing generates double-strand breaks causing deletion, transversion and translocation.
Huang ME, Qin Y, Shang Y, Hao Q, Zhan C, Lian C, Luo S, Liu LD, Zhang S, Zhang Y, Wo Y, Li N, Wu S, Gui T, Wang B, Luo Y, Cai Y, Liu X, Xu Z, Dai P, Li S, Zhang L, Dong J, Wang J, Zheng X, Xu Y, Sun Y, Wu W, Yeap LS, Meng FL. Huang ME, et al. Among authors: cai y. Nat Cell Biol. 2024 Feb;26(2):294-304. doi: 10.1038/s41556-023-01342-2. Epub 2024 Jan 23. Nat Cell Biol. 2024. PMID: 38263276
Chinese herbal formula Tongxie Yaofang granules for diarrhoea-predominant irritable bowel syndrome: a randomised, double-blind, placebo-controlled, phase II trial.
Liang SB, Cheng HJ, Zhang QY, Han M, Li YF, Cao HJ, Yu ZY, Kong LY, Cai YM, An LB, Zhao BT, Xu SS, Yan L, Zhang NW, Jia BY, Liu WF, Niu F, Wu BT, Song JM, Jia SX, Shi MM, Zhang XN, Chung VCH, Robinson N, Liu JP. Liang SB, et al. Among authors: cai ym. BMJ Open. 2025 Jan 27;15(1):e088410. doi: 10.1136/bmjopen-2024-088410. BMJ Open. 2025. PMID: 39870499 Free article. Clinical Trial.
Gene armoring: A way to enhance CAR-T cell function.
Chen Y, Han L, Cai Y, Huang S, Wang M, Li H, Zheng J, Ma B, Wang G. Chen Y, et al. Among authors: cai y. Pharmacol Res. 2025 Jan 25:107622. doi: 10.1016/j.phrs.2025.107622. Online ahead of print. Pharmacol Res. 2025. PMID: 39870184 No abstract available.
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