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Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds.
Li Petri G, El Hassouni B, Sciarrillo R, Funel N, Mantini G, Zeeuw van der Laan EA, Cascioferro S, Avan A, Zucali PA, Zaffaroni N, Lagerweij T, Parrino B, Smid K, Deraco M, Granchi C, Braczko A, Smolenski RT, Matherly LH, Jansen G, Assaraf YG, Diana P, Cloos J, Peters GJ, Minutolo F, Giovannetti E. Li Petri G, et al. Among authors: minutolo f. Br J Cancer. 2020 Aug;123(4):644-656. doi: 10.1038/s41416-020-0912-9. Epub 2020 Jun 4. Br J Cancer. 2020. PMID: 32493992 Free PMC article.
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors.
Asso V, Ghilardi E, Bertini S, Digiacomo M, Granchi C, Minutolo F, Rapposelli S, Bortolato A, Moro S, Macchia M. Asso V, et al. Among authors: minutolo f. ChemMedChem. 2008 Oct;3(10):1530-4. doi: 10.1002/cmdc.200800162. ChemMedChem. 2008. PMID: 18781572 No abstract available.
Study of apoptosis induction and deoxycytidine kinase/cytidine deaminase modulation in the synergistic interaction of a novel ceramide analog and gemcitabine in pancreatic cancer cells.
Giovannetti E, Leon LG, Bertini S, Macchia M, Minutolo F, Funel N, Alecci C, Giancola F, Danesi R, Peters GJ. Giovannetti E, et al. Among authors: minutolo f. Nucleosides Nucleotides Nucleic Acids. 2010 Jun;29(4-6):419-26. doi: 10.1080/15257771003730193. Nucleosides Nucleotides Nucleic Acids. 2010. PMID: 20544530
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Granchi C, Roy S, Giacomelli C, Macchia M, Tuccinardi T, Martinelli A, Lanza M, Betti L, Giannaccini G, Lucacchini A, Funel N, León LG, Giovannetti E, Peters GJ, Palchaudhuri R, Calvaresi EC, Hergenrother PJ, Minutolo F. Granchi C, et al. Among authors: minutolo f. J Med Chem. 2011 Mar 24;54(6):1599-612. doi: 10.1021/jm101007q. Epub 2011 Feb 18. J Med Chem. 2011. PMID: 21332213
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation.
Granchi C, Roy S, De Simone A, Salvetti I, Tuccinardi T, Martinelli A, Macchia M, Lanza M, Betti L, Giannaccini G, Lucacchini A, Giovannetti E, Sciarrillo R, Peters GJ, Minutolo F. Granchi C, et al. Among authors: minutolo f. Eur J Med Chem. 2011 Nov;46(11):5398-407. doi: 10.1016/j.ejmech.2011.08.046. Epub 2011 Sep 8. Eur J Med Chem. 2011. PMID: 21944286
148 results