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Page 1
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.
Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, Hoehn D, Aifantis I. Mullenders J, et al. Among authors: tsirigos a. J Exp Med. 2015 Oct 19;212(11):1833-50. doi: 10.1084/jem.20151323. Epub 2015 Oct 5. J Exp Med. 2015. PMID: 26438359 Free PMC article.
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.
Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, Sánchez-Díaz M, Wang K, Kayembe C, Zhang N, Amoasii L, Choudhuri A, Skok JA, Schober M, Reinberg D, Sicinski P, Schrewe H, Tsirigos A, Zon LI, Aifantis I. Aranda-Orgilles B, et al. Among authors: tsirigos a. Cell Stem Cell. 2016 Dec 1;19(6):784-799. doi: 10.1016/j.stem.2016.08.004. Epub 2016 Aug 25. Cell Stem Cell. 2016. PMID: 27570068 Free PMC article.
Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.
Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, Bayin NS, Frenster JD, Serrano J, Chiriboga L, Baitalmal R, Nanjangud G, Chi AS, Golfinos JG, Wang J, Karajannis MA, Bonneau RA, Reinberg D, Tsirigos A, Zagzag D, Snuderl M, Skok JA, Neubert TA, Placantonakis DG. Modrek AS, et al. Among authors: tsirigos a. Cell Rep. 2017 Oct 31;21(5):1267-1280. doi: 10.1016/j.celrep.2017.10.009. Cell Rep. 2017. PMID: 29091765 Free PMC article.
Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.
Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, Chaudhary K, Munn DH, Tsirigos A, Madaio M, Gabrielsson S, Touma Z, Wither J, De Carvalho DD, McGaha TL. Shinde R, et al. Among authors: tsirigos a. Nat Immunol. 2018 Jun;19(6):571-582. doi: 10.1038/s41590-018-0107-1. Epub 2018 May 14. Nat Immunol. 2018. PMID: 29760532 Free PMC article.
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.
Chen X, Glytsou C, Zhou H, Narang S, Reyna DE, Lopez A, Sakellaropoulos T, Gong Y, Kloetgen A, Yap YS, Wang E, Gavathiotis E, Tsirigos A, Tibes R, Aifantis I. Chen X, et al. Among authors: tsirigos a. Cancer Discov. 2019 Jul;9(7):890-909. doi: 10.1158/2159-8290.CD-19-0117. Epub 2019 May 2. Cancer Discov. 2019. PMID: 31048321 Free PMC article.
3D Chromosomal Landscapes in Hematopoiesis and Immunity.
Kloetgen A, Thandapani P, Tsirigos A, Aifantis I. Kloetgen A, et al. Among authors: tsirigos a. Trends Immunol. 2019 Sep;40(9):809-824. doi: 10.1016/j.it.2019.07.003. Epub 2019 Aug 15. Trends Immunol. 2019. PMID: 31422902 Free PMC article. Review.
RNA Interactions Are Essential for CTCF-Mediated Genome Organization.
Saldaña-Meyer R, Rodriguez-Hernaez J, Escobar T, Nishana M, Jácome-López K, Nora EP, Bruneau BG, Tsirigos A, Furlan-Magaril M, Skok J, Reinberg D. Saldaña-Meyer R, et al. Among authors: tsirigos a. Mol Cell. 2019 Nov 7;76(3):412-422.e5. doi: 10.1016/j.molcel.2019.08.015. Epub 2019 Sep 12. Mol Cell. 2019. PMID: 31522988 Free PMC article.
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks.
Di Giammartino DC, Kloetgen A, Polyzos A, Liu Y, Kim D, Murphy D, Abuhashem A, Cavaliere P, Aronson B, Shah V, Dephoure N, Stadtfeld M, Tsirigos A, Apostolou E. Di Giammartino DC, et al. Among authors: tsirigos a. Nat Cell Biol. 2019 Oct;21(10):1179-1190. doi: 10.1038/s41556-019-0390-6. Epub 2019 Sep 23. Nat Cell Biol. 2019. PMID: 31548608 Free PMC article.
193 results