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N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity.
Keenan B, Finol-Urdaneta RK, Hope A, Bremner JB, Kavallaris M, Lucena-Agell D, Oliva MÁ, Díaz JF, Vine KL. Keenan B, et al. Cancer Cell Int. 2020 May 15;20:170. doi: 10.1186/s12935-020-01251-6. eCollection 2020. Cancer Cell Int. 2020. PMID: 32467666 Free PMC article.
Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface.
Koach J, Holien JK, Massudi H, Carter DR, Ciampa OC, Herath M, Lim T, Seneviratne JA, Milazzo G, Murray JE, McCarroll JA, Liu B, Mayoh C, Keenan B, Stevenson BW, Gorman MA, Bell JL, Doughty L, Hüttelmaier S, Oberthuer A, Fischer M, Gifford AJ, Liu T, Zhang X, Zhu S, Gustafson WC, Haber M, Norris MD, Fletcher JI, Perini G, Parker MW, Cheung BB, Marshall GM. Koach J, et al. Among authors: keenan b. Cancer Res. 2019 Nov 1;79(21):5652-5667. doi: 10.1158/0008-5472.CAN-19-1112. Epub 2019 Sep 9. Cancer Res. 2019. PMID: 31501192
Comparative analysis of sleep physiology using qualitative and quantitative criteria for insomnia symptoms.
Lee R, Larson O, Dhaliwal S, Moon K, Gerardy B, de Chazal P, Cistulli PA, Chen NH, Han F, Yun Li Q, Maislin G, McArdle N, Penzel T, Schwab RJ, Tufik S, Magalang UJ, Singh B, Gislason T, Pack AI, Keenan BT, Younes M, Gehrman P. Lee R, et al. Among authors: keenan bt. Sleep. 2024 Dec 23:zsae301. doi: 10.1093/sleep/zsae301. Online ahead of print. Sleep. 2024. PMID: 39713965
Impact of mid-Z gas fill on dynamics and performance of shock-driven implosions at the OMEGA laser.
Gatu Johnson M, Adrian PJ, Appelbe BD, Crilly AJ, Forrest CJ, Glebov VY, Green LM, Haines BM, Kabadi NV, Kagan G, Keenan BD, Kunimune J, Li CK, Mannion OM, Petrasso RD, Séguin FH, Sio HW, Stoeckl C, Sutcliffe GD, Taitano WT, Frenje JA. Gatu Johnson M, et al. Among authors: keenan bd. Phys Rev E. 2024 Jun;109(6-2):065201. doi: 10.1103/PhysRevE.109.065201. Phys Rev E. 2024. PMID: 39020911
306 results