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696 results

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A nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury: A randomised, placebo-controlled pilot study.
Ryan J, Bayliffe AI, McAuley DF, Yeung J, Thickett DR, Howells PA, O'Donnell C, Vassallo AM, Wright TJ, McKie E, Hardes K, Summers C, Shields MO, Powley W, Wilson R, Lazaar AL, Fowler A, Perkins GD. Ryan J, et al. Among authors: summers c. Eur J Anaesthesiol. 2020 Nov;37(11):1014-1024. doi: 10.1097/EJA.0000000000001245. Eur J Anaesthesiol. 2020. PMID: 32467417 Free PMC article. Clinical Trial.
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury.
Proudfoot A, Bayliffe A, O'Kane CM, Wright T, Serone A, Bareille PJ, Brown V, Hamid UI, Chen Y, Wilson R, Cordy J, Morley P, de Wildt R, Elborn S, Hind M, Chilvers ER, Griffiths M, Summers C, McAuley DF. Proudfoot A, et al. Among authors: summers c. Thorax. 2018 Aug;73(8):723-730. doi: 10.1136/thoraxjnl-2017-210305. Epub 2018 Jan 29. Thorax. 2018. PMID: 29382797 Free PMC article. Clinical Trial.
C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling.
Wood AJ, Vassallo AM, Ruchaud-Sparagano MH, Scott J, Zinnato C, Gonzalez-Tejedo C, Kishore K, D'Santos CS, Simpson AJ, Menon DK, Summers C, Chilvers ER, Okkenhaug K, Morris AC. Wood AJ, et al. Among authors: summers c. JCI Insight. 2020 Aug 6;5(15):e137029. doi: 10.1172/jci.insight.137029. JCI Insight. 2020. PMID: 32634128 Free PMC article.
RAND appropriateness panel to determine the applicability of UK guidelines on the management of acute respiratory distress syndrome (ARDS) and other strategies in the context of the COVID-19 pandemic.
Griffiths M, Meade S, Summers C, McAuley DF, Proudfoot A, Baladia MM, Dark PM, Diomede K, Finney SJ, Forni LG, Meadows C, Naldrett IA, Patel B, Perkins GD, Samaan MA, Sharifi L, Suntharalingam G, Tarmey NT, Young HF, Wise MP, Irving PM. Griffiths M, et al. Among authors: summers c. Thorax. 2022 Feb;77(2):129-135. doi: 10.1136/thoraxjnl-2021-216904. Epub 2021 May 27. Thorax. 2022. PMID: 34045363
Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial.
McNamee JJ, Gillies MA, Barrett NA, Perkins GD, Tunnicliffe W, Young D, Bentley A, Harrison DA, Brodie D, Boyle AJ, Millar JE, Szakmany T, Bannard-Smith J, Tully RP, Agus A, McDowell C, Jackson C, McAuley DF; REST Investigators. McNamee JJ, et al. JAMA. 2021 Sep 21;326(11):1013-1023. doi: 10.1001/jama.2021.13374. JAMA. 2021. PMID: 34463700 Free PMC article. Clinical Trial.
Safety and efficacy of multipotent adult progenitor cells in acute respiratory distress syndrome (MUST-ARDS): a multicentre, randomised, double-blind, placebo-controlled phase 1/2 trial.
Bellingan G, Jacono F, Bannard-Smith J, Brealey D, Meyer N, Thickett D, Young D, Bentley A, McVerry BJ, Wunderink RG, Doerschug KC, Summers C, Rojas M, Ting A, Jenkins ED. Bellingan G, et al. Among authors: summers c. Intensive Care Med. 2022 Jan;48(1):36-44. doi: 10.1007/s00134-021-06570-4. Epub 2021 Nov 23. Intensive Care Med. 2022. PMID: 34811567 Free PMC article. Clinical Trial.
Towards a biological definition of ARDS: are treatable traits the solution?
Bos LDJ, Laffey JG, Ware LB, Heijnen NFL, Sinha P, Patel B, Jabaudon M, Bastarache JA, McAuley DF, Summers C, Calfee CS, Shankar-Hari M. Bos LDJ, et al. Among authors: summers c. Intensive Care Med Exp. 2022 Mar 11;10(1):8. doi: 10.1186/s40635-022-00435-w. Intensive Care Med Exp. 2022. PMID: 35274164 Free PMC article. Review.
696 results