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Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H. Park M, et al. Among authors: yanagisawa m. Sci Rep. 2020 May 26;10(1):8676. doi: 10.1038/s41598-020-65647-0. Sci Rep. 2020. PMID: 32457359 Free PMC article.
An essential role for orexins in emergence from general anesthesia.
Kelz MB, Sun Y, Chen J, Cheng Meng Q, Moore JT, Veasey SC, Dixon S, Thornton M, Funato H, Yanagisawa M. Kelz MB, et al. Among authors: yanagisawa m. Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1309-14. doi: 10.1073/pnas.0707146105. Epub 2008 Jan 14. Proc Natl Acad Sci U S A. 2008. PMID: 18195361 Free PMC article.
Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture.
Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami K, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Matsuki T, et al. Among authors: yanagisawa m. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4459-64. doi: 10.1073/pnas.0811126106. Epub 2009 Feb 25. Proc Natl Acad Sci U S A. 2009. PMID: 19246384 Free PMC article.
Loss of Goosecoid-like and DiGeorge syndrome critical region 14 in interpeduncular nucleus results in altered regulation of rapid eye movement sleep.
Funato H, Sato M, Sinton CM, Gautron L, Williams SC, Skach A, Elmquist JK, Skoultchi AI, Yanagisawa M. Funato H, et al. Among authors: yanagisawa m. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18155-60. doi: 10.1073/pnas.1012764107. Epub 2010 Oct 4. Proc Natl Acad Sci U S A. 2010. PMID: 20921407 Free PMC article.
Identification of mutations through dominant screening for obesity using C57BL/6 substrains.
Hossain MS, Asano F, Fujiyama T, Miyoshi C, Sato M, Ikkyu A, Kanno S, Hotta N, Kakizaki M, Honda T, Kim SJ, Komiya H, Miura I, Suzuki T, Kobayashi K, Kaneda H, Kumar V, Takahashi JS, Wakana S, Funato H, Yanagisawa M. Hossain MS, et al. Among authors: yanagisawa m. Sci Rep. 2016 Sep 2;6:32453. doi: 10.1038/srep32453. Sci Rep. 2016. PMID: 27585985 Free PMC article.
Forward-genetics analysis of sleep in randomly mutagenized mice.
Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M. Funato H, et al. Among authors: yanagisawa m. Nature. 2016 Nov 17;539(7629):378-383. doi: 10.1038/nature20142. Epub 2016 Nov 2. Nature. 2016. PMID: 27806374 Free PMC article.
Peripherally administered orexin improves survival of mice with endotoxin shock.
Ogawa Y, Irukayama-Tomobe Y, Murakoshi N, Kiyama M, Ishikawa Y, Hosokawa N, Tominaga H, Uchida S, Kimura S, Kanuka M, Morita M, Hamada M, Takahashi S, Hayashi Y, Yanagisawa M. Ogawa Y, et al. Among authors: yanagisawa m. Elife. 2016 Dec 30;5:e21055. doi: 10.7554/eLife.21055. Elife. 2016. PMID: 28035899 Free PMC article.
1,187 results