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Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species.
Yang W, Wang Y, Lai A, Clark CG, Corte JR, Fang T, Gilligan PJ, Jeon Y, Pabbisetty KB, Rampulla RA, Mathur A, Kaspady M, Neithnadka PR, Arumugam A, Raju S, Rossi KA, Myers JE Jr, Sheriff S, Lou Z, Zheng JJ, Chacko SA, Bozarth JM, Wu Y, Crain EJ, Wong PC, Seiffert DA, Luettgen JM, Lam PYS, Wexler RR, Ewing WR. Yang W, et al. Among authors: arumugam a. J Med Chem. 2020 Jul 9;63(13):7226-7242. doi: 10.1021/acs.jmedchem.0c00464. Epub 2020 Jun 17. J Med Chem. 2020. PMID: 32456431
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
Zheng BZ, D'Andrea SV, Hanumegowda U, Knipe JO, Mosure K, Zhuo X, Lemm JA, Liu M, Rigat KL, Wang YK, Fang H, Poronsky C, Cutrone J, Wu DR, Arunachalam PN, Balapragalathan TJ, Arumugam A, Mathur A, Meanwell NA, Gao M, Roberts SB, Kadow JF. Zheng BZ, et al. Among authors: arumugam a. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3294-3300. doi: 10.1016/j.bmcl.2017.06.024. Epub 2017 Jun 11. Bioorg Med Chem Lett. 2017. PMID: 28633899
Comparing and assessing physical activity and sedentary behaviour guidelines for different populations with and without chronic conditions and/or disabilities: a systematic review protocol.
Arumugam A, Shalash RJ, Qadah RM, Alsaafin N, Mohammad Zadeh SA, Chaput JP, Pesola AJ, Kumaran D S, Moss SJ, Veldsman T, Ramakrishnan S, Regan R, Arora E, A SA, Raghunathan MRK, Al Tunaiji H, Baltatu OC, Nassis GP, McDonough S, Dempsey PC, Häger C. Arumugam A, et al. BMJ Open Sport Exerc Med. 2024 Dec 22;10(4):e002362. doi: 10.1136/bmjsem-2024-002362. eCollection 2024. BMJ Open Sport Exerc Med. 2024. PMID: 39720153 Free PMC article.
Alcohol-attributed disease burden and formal alcohol policies in the Nordic countries (1990-2019): an analysis using the Global Burden of Disease Study 2019.
van der Velde L, Shabaan AN, Månsson A, Wennberg P, Allebeck P, Karlsson TG, Flodin P, Eikemo TA, Skrindo Knudsen AK, de Soysa I, Skogen JC; GBD 2019 Nordic Alcohol Collaborators; Gissler M, McGrath JJ, Sigfusdottir ID, Sigurvinsdottir R, Pasovic M, Danielsson AK, Agardh EE. van der Velde L, et al. Eur J Public Health. 2024 Dec 2:ckae195. doi: 10.1093/eurpub/ckae195. Online ahead of print. Eur J Public Health. 2024. PMID: 39673429
179 results