Rots MG - Search Results

1

KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and is Resilient to TGFβ1 Activation.

Gjaltema RAF, Goubert D, Huisman C, Pilar García Tobilla CD, Koncz M, Jellema PG, Wu D, Brouwer U, Kiss A, Verschure PJ, Bank RA, Rots MG. Gjaltema RAF, et al. Among authors: rots mg. Int J Mol Sci. 2020 May 21;21(10):3634. doi: 10.3390/ijms21103634. Int J Mol Sci. 2020. PMID: 32455614 Free PMC article.

2

Step into the groove: engineered transcription factors as modulators of gene expression.

Visser AE, Verschure PJ, Gommans WM, Haisma HJ, Rots MG. Visser AE, et al. Among authors: rots mg. Adv Genet. 2006;56:131-61. doi: 10.1016/S0065-2660(06)56004-3. Adv Genet. 2006. PMID: 16735157 Review.

3

Step out of the groove: epigenetic gene control systems and engineered transcription factors.

Verschure PJ, Visser AE, Rots MG. Verschure PJ, et al. Among authors: rots mg. Adv Genet. 2006;56:163-204. doi: 10.1016/S0065-2660(06)56005-5. Adv Genet. 2006. PMID: 16735158 Review.

4

Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.

van der Gun BTF, Wasserkort R, Monami A, Jeltsch A, Raskó T, Ślaska-Kiss K, Cortese R, Rots MG, de Leij LFMH, Ruiters MHJ, Kiss A, Weinhold E, McLaughlin PMJ. van der Gun BTF, et al. Among authors: rots mg. Int J Cancer. 2008 Jul 15;123(2):484-489. doi: 10.1002/ijc.23476. Int J Cancer. 2008. PMID: 18398839

5

Targeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule.

van der Gun BT, Maluszynska-Hoffman M, Kiss A, Arendzen AJ, Ruiters MH, McLaughlin PM, Weinhold E, Rots MG. van der Gun BT, et al. Among authors: rots mg. Bioconjug Chem. 2010 Jul 21;21(7):1239-45. doi: 10.1021/bc1000388. Bioconjug Chem. 2010. PMID: 20593890 Free PMC article.

6

Modulation of gene expression using zinc finger-based artificial transcription factors.

Stolzenburg S, Bilsland A, Keith WN, Rots MG. Stolzenburg S, et al. Among authors: rots mg. Methods Mol Biol. 2010;649:117-32. doi: 10.1007/978-1-60761-753-2_7. Methods Mol Biol. 2010. PMID: 20680831

7

Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.

de Groote ML, Verschure PJ, Rots MG. de Groote ML, et al. Among authors: rots mg. Nucleic Acids Res. 2012 Nov;40(21):10596-613. doi: 10.1093/nar/gks863. Epub 2012 Sep 21. Nucleic Acids Res. 2012. PMID: 23002135 Free PMC article. Review.

8

Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer.

van der Gun BT, Huisman C, Stolzenburg S, Kazemier HG, Ruiters MH, Blancafort P, Rots MG. van der Gun BT, et al. Among authors: rots mg. Br J Cancer. 2013 Mar 5;108(4):881-6. doi: 10.1038/bjc.2013.45. Epub 2013 Feb 12. Br J Cancer. 2013. PMID: 23403823 Free PMC article.

9

Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors.

Huisman C, Wisman GB, Kazemier HG, van Vugt MA, van der Zee AG, Schuuring E, Rots MG. Huisman C, et al. Among authors: rots mg. Mol Oncol. 2013 Jun;7(3):669-79. doi: 10.1016/j.molonc.2013.02.017. Epub 2013 Mar 5. Mol Oncol. 2013. PMID: 23522960 Free PMC article.

10

Towards sustained silencing of HER2/neu in cancer by epigenetic editing.

Falahi F, Huisman C, Kazemier HG, van der Vlies P, Kok K, Hospers GA, Rots MG. Falahi F, et al. Among authors: rots mg. Mol Cancer Res. 2013 Sep;11(9):1029-39. doi: 10.1158/1541-7786.MCR-12-0567. Epub 2013 Jun 27. Mol Cancer Res. 2013. PMID: 23814024

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