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Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
Li Y, Zhao J, Gutgesell LM, Shen Z, Ratia K, Dye K, Dubrovskyi O, Zhao H, Huang F, Tonetti DA, Thatcher GRJ, Xiong R. Li Y, et al. Among authors: zhao j, zhao h. J Med Chem. 2020 Jul 9;63(13):7186-7210. doi: 10.1021/acs.jmedchem.0c00456. Epub 2020 Jun 15. J Med Chem. 2020. PMID: 32453591 Free PMC article.
Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer.
Molloy ME, White BE, Gherezghiher T, Michalsen BT, Xiong R, Patel H, Zhao H, Maximov PY, Jordan VC, Thatcher GR, Tonetti DA. Molloy ME, et al. Among authors: zhao h. Mol Cancer Ther. 2014 Nov;13(11):2515-26. doi: 10.1158/1535-7163.MCT-14-0319. Epub 2014 Sep 9. Mol Cancer Ther. 2014. PMID: 25205655 Free PMC article.
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer.
Lu Y, Gutgesell LM, Xiong R, Zhao J, Li Y, Rosales CI, Hollas M, Shen Z, Gordon-Blake J, Dye K, Wang Y, Lee S, Chen H, He D, Dubrovyskyii O, Zhao H, Huang F, Lasek AW, Tonetti DA, Thatcher GRJ. Lu Y, et al. Among authors: zhao j, zhao h. J Med Chem. 2019 Dec 26;62(24):11301-11323. doi: 10.1021/acs.jmedchem.9b01580. Epub 2019 Dec 10. J Med Chem. 2019. PMID: 31746603 Free PMC article.
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