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Expanded Structure-Activity Studies of Lipoxazolidinone Antibiotics.
Robinson KR, Mills JJ, Pierce JG. Robinson KR, et al. Among authors: mills jj. ACS Med Chem Lett. 2019 Feb 28;10(3):374-377. doi: 10.1021/acsmedchemlett.9b00015. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891143 Free PMC article.
Enantiospecific Synthesis of β-Substituted Tryptamines.
Rubin HN, Van Hecke K, Mills JJ, Cockrell J, Morgan JB. Rubin HN, et al. Among authors: mills jj. Org Lett. 2017 Sep 15;19(18):4976-4979. doi: 10.1021/acs.orglett.7b02474. Epub 2017 Sep 7. Org Lett. 2017. PMID: 28880094
Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors.
Teuscher KB, Mills JJ, Tian J, Han C, Meyers KM, Sai J, South TM, Crow MM, Van Meveren M, Sensintaffar JL, Zhao B, Amporndanai K, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW. Teuscher KB, et al. Among authors: mills jj. J Med Chem. 2023 Dec 28;66(24):16783-16806. doi: 10.1021/acs.jmedchem.3c01529. Epub 2023 Dec 12. J Med Chem. 2023. PMID: 38085679
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core.
Tian J, Teuscher KB, Aho ER, Alvarado JR, Mills JJ, Meyers KM, Gogliotti RD, Han C, Macdonald JD, Sai J, Shaw JG, Sensintaffar JL, Zhao B, Rietz TA, Thomas LR, Payne WG, Moore WJ, Stott GM, Kondo J, Inoue M, Coffey RJ, Tansey WP, Stauffer SR, Lee T, Fesik SW. Tian J, et al. Among authors: mills jj. J Med Chem. 2020 Jan 23;63(2):656-675. doi: 10.1021/acs.jmedchem.9b01608. Epub 2020 Jan 7. J Med Chem. 2020. PMID: 31858797 Free PMC article.
Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization.
Teuscher KB, Meyers KM, Wei Q, Mills JJ, Tian J, Alvarado J, Sai J, Van Meveren M, South TM, Rietz TA, Zhao B, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW. Teuscher KB, et al. Among authors: mills jj. J Med Chem. 2022 Apr 28;65(8):6287-6312. doi: 10.1021/acs.jmedchem.2c00195. Epub 2022 Apr 18. J Med Chem. 2022. PMID: 35436124 Free PMC article.
33 results