Signer RAJ - Search Results

1

Hematopoietic stem cell regulation by the proteostasis network.

Chua BA, Signer RAJ. Chua BA, et al. Among authors: signer raj. Curr Opin Hematol. 2020 Jul;27(4):254-263. doi: 10.1097/MOH.0000000000000591. Curr Opin Hematol. 2020. PMID: 32452878 Free PMC article. Review.

2

Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines.

Porter SN, Cluster AS, Signer RAJ, Voigtmann J, Monlish DA, Schuettpelz LG, Magee JA. Porter SN, et al. Among authors: signer raj. Stem Cell Reports. 2016 Jun 14;6(6):806-814. doi: 10.1016/j.stemcr.2016.04.008. Epub 2016 May 12. Stem Cell Reports. 2016. PMID: 27185281 Free PMC article.

3

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs.

Signer RA, Qi L, Zhao Z, Thompson D, Sigova AA, Fan ZP, DeMartino GN, Young RA, Sonenberg N, Morrison SJ. Signer RA, et al. Genes Dev. 2016 Aug 1;30(15):1698-703. doi: 10.1101/gad.282756.116. Epub 2016 Aug 4. Genes Dev. 2016. PMID: 27492367 Free PMC article.

4

Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function.

Mgbemena VE, Signer RAJ, Wijayatunge R, Laxson T, Morrison SJ, Ross TS. Mgbemena VE, et al. Among authors: signer raj. Cell Rep. 2017 Jan 24;18(4):947-960. doi: 10.1016/j.celrep.2016.12.075. Cell Rep. 2017. PMID: 28122244 Free PMC article.

5

Cell-type-specific quantification of protein synthesis in vivo.

Hidalgo San Jose L, Signer RAJ. Hidalgo San Jose L, et al. Among authors: signer raj. Nat Protoc. 2019 Feb;14(2):441-460. doi: 10.1038/s41596-018-0100-z. Nat Protoc. 2019. PMID: 30610239 Free PMC article.

6

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.

Hidalgo San Jose L, Sunshine MJ, Dillingham CH, Chua BA, Kruta M, Hong Y, Hatters DM, Signer RAJ. Hidalgo San Jose L, et al. Among authors: signer raj. Cell Rep. 2020 Jan 7;30(1):69-80.e6. doi: 10.1016/j.celrep.2019.12.003. Cell Rep. 2020. PMID: 31914399 Free PMC article.

7

Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells.

Chua BA, Van Der Werf I, Jamieson C, Signer RAJ. Chua BA, et al. Among authors: signer raj. Cell Stem Cell. 2020 Feb 6;26(2):138-159. doi: 10.1016/j.stem.2020.01.005. Cell Stem Cell. 2020. PMID: 32032524 Free PMC article. Review.

8

ERADicating stem cells from their niche.

Lam K, Signer RAJ. Lam K, et al. Among authors: signer raj. Nat Cell Biol. 2020 Oct;22(10):1155-1157. doi: 10.1038/s41556-020-00585-7. Nat Cell Biol. 2020. PMID: 32958855 Free PMC article.

9

Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis.

Magee JA, Signer RAJ. Magee JA, et al. Among authors: signer raj. Stem Cell Reports. 2021 Jan 12;16(1):20-28. doi: 10.1016/j.stemcr.2020.11.017. Stem Cell Reports. 2021. PMID: 33440178 Free PMC article.

10

Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging.

Kruta M, Sunshine MJ, Chua BA, Fu Y, Chawla A, Dillingham CH, Hidalgo San Jose L, De Jong B, Zhou FJ, Signer RAJ. Kruta M, et al. Among authors: signer raj. Cell Stem Cell. 2021 Nov 4;28(11):1950-1965.e6. doi: 10.1016/j.stem.2021.07.009. Epub 2021 Aug 12. Cell Stem Cell. 2021. PMID: 34388375 Free PMC article.

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