Ding TB - Search Results

1

Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer.

Deng Y, Hu JC, He SH, Lou B, Ding TB, Yang JT, Mo MG, Ye DY, Zhou L, Jiang XC, Yu K, Dong JB. Deng Y, et al. Among authors: ding tb. Acta Pharmacol Sin. 2021 Jan;42(1):149-159. doi: 10.1038/s41401-020-0419-1. Epub 2020 May 25. Acta Pharmacol Sin. 2021. PMID: 32451413 Free PMC article.

2

Sphingomyelin synthase overexpression increases cholesterol accumulation and decreases cholesterol secretion in liver cells.

Yan N, Ding T, Dong J, Li Y, Wu M. Yan N, et al. Lipids Health Dis. 2011 Mar 21;10:46. doi: 10.1186/1476-511X-10-46. Lipids Health Dis. 2011. PMID: 21418611 Free PMC article.

3

Subcellular targeting domains of sphingomyelin synthase 1 and 2.

Yeang C, Ding T, Chirico WJ, Jiang XC. Yeang C, et al. Nutr Metab (Lond). 2011 Dec 14;8:89. doi: 10.1186/1743-7075-8-89. Nutr Metab (Lond). 2011. PMID: 22168400 Free PMC article.

4

Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression.

Li Y, Dong J, Ding T, Kuo MS, Cao G, Jiang XC, Li Z. Li Y, et al. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1513-20. doi: 10.1161/ATVBAHA.113.301498. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640498 Free PMC article.

5

Identification of small molecule sphingomyelin synthase inhibitors.

Deng X, Lin F, Zhang Y, Li Y, Zhou L, Lou B, Li Y, Dong J, Ding T, Jiang X, Wang R, Ye D. Deng X, et al. Eur J Med Chem. 2014 Feb 12;73:1-7. doi: 10.1016/j.ejmech.2013.12.002. Epub 2013 Dec 14. Eur J Med Chem. 2014. PMID: 24374347

6

Pharmacologic inhibition of sphingomyelin synthase (SMS) activity reduces apolipoprotein-B secretion from hepatocytes and attenuates endotoxin-mediated macrophage inflammation.

Lou B, Dong J, Li Y, Ding T, Bi T, Li Y, Deng X, Ye D, Jiang XC. Lou B, et al. PLoS One. 2014 Jul 17;9(7):e102641. doi: 10.1371/journal.pone.0102641. eCollection 2014. PLoS One. 2014. PMID: 25032960 Free PMC article.

7

All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.

Ding T, Kabir I, Li Y, Lou C, Yazdanyar A, Xu J, Dong J, Zhou H, Park T, Boutjdir M, Li Z, Jiang XC. Ding T, et al. J Lipid Res. 2015 Mar;56(3):537-545. doi: 10.1194/jlr.M054627. Epub 2015 Jan 20. J Lipid Res. 2015. PMID: 25605874 Free PMC article.

8

Deficiency in lysophosphatidylcholine acyltransferase 3 reduces plasma levels of lipids by reducing lipid absorption in mice.

Li Z, Jiang H, Ding T, Lou C, Bui HH, Kuo MS, Jiang XC. Li Z, et al. Gastroenterology. 2015 Nov;149(6):1519-29. doi: 10.1053/j.gastro.2015.07.012. Epub 2015 Jul 27. Gastroenterology. 2015. PMID: 26226572 Free PMC article.

9

Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.

Li YL, Qi XY, Jiang H, Deng XD, Dong YP, Ding TB, Zhou L, Men P, Chu Y, Wang RX, Jiang XC, Ye DY. Li YL, et al. Among authors: ding tb. Bioorg Med Chem. 2015 Sep 15;23(18):6173-84. doi: 10.1016/j.bmc.2015.07.060. Epub 2015 Jul 30. Bioorg Med Chem. 2015. PMID: 26314925

10

The flavonoid TL-2-8 induces cell death and immature mitophagy in breast cancer cells via abrogating the function of the AHA1/Hsp90 complex.

Liu HJ, Jiang XX, Guo YZ, Sun FH, Kou XH, Bao Y, Zhang ZQ, Lin ZH, Ding TB, Jiang L, Lei XS, Yang YH. Liu HJ, et al. Among authors: ding tb. Acta Pharmacol Sin. 2017 Oct;38(10):1381-1393. doi: 10.1038/aps.2017.9. Epub 2017 May 1. Acta Pharmacol Sin. 2017. PMID: 28504248 Free PMC article.

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