Melgari D - Search Results

1

Microtubule polymerization state and clathrin-dependent internalization regulate dynamics of cardiac potassium channel: Microtubule and clathrin control of K_V1.5 channel.

Melgari D, Barbier C, Dilanian G, Rücker-Martin C, Doisne N, Coulombe A, Hatem SN, Balse E. Melgari D, et al. J Mol Cell Cardiol. 2020 Jul;144:127-139. doi: 10.1016/j.yjmcc.2020.05.004. Epub 2020 May 20. J Mol Cell Cardiol. 2020. PMID: 32445844 Free article.

2

hERG potassium channel inhibition by ivabradine requires channel gating.

Melgari D, Brack KE, Zhang Y, El Harchi A, Mitcheson JS, Dempsey CE, Ng GA, Hancox JC. Melgari D, et al. J Mol Cell Cardiol. 2015 Oct;87:126-8. doi: 10.1016/j.yjmcc.2015.08.002. Epub 2015 Aug 11. J Mol Cell Cardiol. 2015. PMID: 26275355 No abstract available.

3

Distinct calcium/calmodulin-dependent serine protein kinase domains control cardiac sodium channel membrane expression and focal adhesion anchoring.

Beuriot A, Eichel CA, Dilanian G, Louault F, Melgari D, Doisne N, Coulombe A, Hatem SN, Balse E. Beuriot A, et al. Among authors: melgari d. Heart Rhythm. 2020 May;17(5 Pt A):786-794. doi: 10.1016/j.hrthm.2019.12.019. Epub 2020 Jan 3. Heart Rhythm. 2020. PMID: 31904424 Free article.

4

Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide.

Melgari D, Zhang Y, El Harchi A, Dempsey CE, Hancox JC. Melgari D, et al. J Mol Cell Cardiol. 2015 Sep;86:42-53. doi: 10.1016/j.yjmcc.2015.06.021. Epub 2015 Jul 6. J Mol Cell Cardiol. 2015. PMID: 26159617 Free PMC article.

5

Action potential clamp and pharmacology of the variant 1 Short QT Syndrome T618I hERG K⁺ channel.

El Harchi A, Melgari D, Zhang YH, Zhang H, Hancox JC. El Harchi A, et al. Among authors: melgari d. PLoS One. 2012;7(12):e52451. doi: 10.1371/journal.pone.0052451. Epub 2012 Dec 26. PLoS One. 2012. PMID: 23300672 Free PMC article.

6

Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration.

Melgari D, Du C, El Harchi A, Zhang Y, Hancox JC. Melgari D, et al. Physiol Rep. 2014 Oct 15;2(10):e12165. doi: 10.14814/phy2.12165. Print 2014 Oct 1. Physiol Rep. 2014. PMID: 25318749 Free PMC article.

7

hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine.

Melgari D, Brack KE, Zhang C, Zhang Y, El Harchi A, Mitcheson JS, Dempsey CE, Ng GA, Hancox JC. Melgari D, et al. J Am Heart Assoc. 2015 Apr 24;4(4):e001813. doi: 10.1161/JAHA.115.001813. J Am Heart Assoc. 2015. PMID: 25911606 Free PMC article.

8

hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes.

Hancox JC, Melgari D, Dempsey CE, Brack KE, Mitcheson J, Ng GA. Hancox JC, et al. Among authors: melgari d. Ther Adv Drug Saf. 2015 Aug;6(4):177-9. doi: 10.1177/2042098615595546. Ther Adv Drug Saf. 2015. PMID: 26301071 Free PMC article. No abstract available.

9

Letter by Melgari et al Regarding Article, "Ivabradine: Role in the Chronic Heart Failure Armamentarium".

Melgari D, Ng GA, Hancox JC. Melgari D, et al. Circulation. 2016 Sep 27;134(13):e296-7. doi: 10.1161/CIRCULATIONAHA.116.023752. Circulation. 2016. PMID: 27672201 No abstract available.

10

Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence.

Lei CL, Clerx M, Beattie KA, Melgari D, Hancox JC, Gavaghan DJ, Polonchuk L, Wang K, Mirams GR. Lei CL, et al. Among authors: melgari d. Biophys J. 2019 Dec 17;117(12):2455-2470. doi: 10.1016/j.bpj.2019.07.030. Epub 2019 Jul 25. Biophys J. 2019. PMID: 31451180 Free PMC article.

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