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Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates.
Maxan A, Sciacca G, Alpaugh M, Tao Z, Breger L, Dehay B, Ling Z, Chuan Q, Cisbani G, Masnata M, Salem S, Lacroix S, Oueslati A, Bezard E, Cicchetti F. Maxan A, et al. Among authors: cisbani g. Neurobiol Dis. 2020 Jul;141:104951. doi: 10.1016/j.nbd.2020.104951. Epub 2020 May 18. Neurobiol Dis. 2020. PMID: 32439599 Free article.
Mutant huntingtin is present in neuronal grafts in Huntington disease patients.
Cicchetti F, Lacroix S, Cisbani G, Vallières N, Saint-Pierre M, St-Amour I, Tolouei R, Skepper JN, Hauser RA, Mantovani D, Barker RA, Freeman TB. Cicchetti F, et al. Among authors: cisbani g. Ann Neurol. 2014 Jul;76(1):31-42. doi: 10.1002/ana.24174. Epub 2014 Jun 6. Ann Neurol. 2014. PMID: 24798518
Human-to-mouse prion-like propagation of mutant huntingtin protein.
Jeon I, Cicchetti F, Cisbani G, Lee S, Li E, Bae J, Lee N, Li L, Im W, Kim M, Kim HS, Oh SH, Kim TA, Ko JJ, Aubé B, Oueslati A, Kim YJ, Song J. Jeon I, et al. Among authors: cisbani g. Acta Neuropathol. 2016 Oct;132(4):577-92. doi: 10.1007/s00401-016-1582-9. Epub 2016 May 24. Acta Neuropathol. 2016. PMID: 27221146 Free PMC article.
Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease.
Cisbani G, Drouin-Ouellet J, Gibrat C, Saint-Pierre M, Lagacé M, Badrinarayanan S, Lavallée-Bourget MH, Charest J, Chabrat A, Boivin L, Lebel M, Bousquet M, Lévesque M, Cicchetti F. Cisbani G, et al. Neurobiol Dis. 2015 Oct;82:430-444. doi: 10.1016/j.nbd.2015.07.012. Epub 2015 Jul 29. Neurobiol Dis. 2015. PMID: 26232588
Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology.
Drouin-Ouellet J, Sawiak SJ, Cisbani G, Lagacé M, Kuan WL, Saint-Pierre M, Dury RJ, Alata W, St-Amour I, Mason SL, Calon F, Lacroix S, Gowland PA, Francis ST, Barker RA, Cicchetti F. Drouin-Ouellet J, et al. Among authors: cisbani g. Ann Neurol. 2015 Aug;78(2):160-77. doi: 10.1002/ana.24406. Epub 2015 Apr 9. Ann Neurol. 2015. PMID: 25866151
45 results