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Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome.
Sci Transl Med. 2020 May 20;12(544):eaam8572. doi: 10.1126/scitranslmed.aam8572.
Sci Transl Med. 2020.
PMID: 32434848
Free PMC article.
β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X.
Stoppel LJ, Auerbach BD, Senter RK, Preza AR, Lefkowitz RJ, Bear MF.
Stoppel LJ, et al.
Cell Rep. 2017 Mar 21;18(12):2807-2814. doi: 10.1016/j.celrep.2017.02.075.
Cell Rep. 2017.
PMID: 28329674
Free PMC article.
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Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion.
Tian D, Stoppel LJ, Heynen AJ, Lindemann L, Jaeschke G, Mills AA, Bear MF.
Tian D, et al. Among authors: stoppel lj.
Nat Neurosci. 2015 Feb;18(2):182-4. doi: 10.1038/nn.3911. Epub 2015 Jan 12.
Nat Neurosci. 2015.
PMID: 25581360
Free PMC article.
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R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice.
Stoppel LJ, Kazdoba TM, Schaffler MD, Preza AR, Heynen A, Crawley JN, Bear MF.
Stoppel LJ, et al.
Neuropsychopharmacology. 2018 Feb;43(3):513-524. doi: 10.1038/npp.2017.236. Epub 2017 Oct 6.
Neuropsychopharmacology. 2018.
PMID: 28984295
Free PMC article.
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