Carette JE - Search Results

1

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling.

Dubey R, van Kerkhof P, Jordens I, Malinauskas T, Pusapati GV, McKenna JK, Li D, Carette JE, Ho M, Siebold C, Maurice M, Lebensohn AM, Rohatgi R. Dubey R, et al. Among authors: carette je. Elife. 2020 May 20;9:e54469. doi: 10.7554/eLife.54469. Elife. 2020. PMID: 32432544 Free PMC article.

2

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, van Diemen FR, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S. Tsvetkov P, et al. Among authors: carette je. Elife. 2015 Sep 1;4:e08467. doi: 10.7554/eLife.08467. Elife. 2015. PMID: 26327695 Free PMC article.

3

A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.

Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH. Gowen BG, et al. Among authors: carette je. Elife. 2015 Nov 13;4:e08474. doi: 10.7554/eLife.08474. Elife. 2015. PMID: 26565589 Free PMC article.

4

Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1.

Dubey R, Lebensohn AM, Bahrami-Nejad Z, Marceau C, Champion M, Gevaert O, Sikic BI, Carette JE, Rohatgi R. Dubey R, et al. Among authors: carette je. Cancer Res. 2016 Oct 1;76(19):5810-5821. doi: 10.1158/0008-5472.CAN-16-0716. Epub 2016 Aug 8. Cancer Res. 2016. PMID: 27503929 Free PMC article.

5

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling.

Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R. Lebensohn AM, et al. Among authors: carette je. Elife. 2016 Dec 20;5:e21459. doi: 10.7554/eLife.21459. Elife. 2016. PMID: 27996937 Free PMC article.

6

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens.

Patel BB, Lebensohn AM, Pusapati GV, Carette JE, Salzman J, Rohatgi R. Patel BB, et al. Among authors: carette je. PLoS One. 2019 Jan 29;14(1):e0198463. doi: 10.1371/journal.pone.0198463. eCollection 2019. PLoS One. 2019. PMID: 30695034 Free PMC article.

7

Lipid droplets can promote drug accumulation and activation.

Dubey R, Stivala CE, Nguyen HQ, Goo YH, Paul A, Carette JE, Trost BM, Rohatgi R. Dubey R, et al. Among authors: carette je. Nat Chem Biol. 2020 Feb;16(2):206-213. doi: 10.1038/s41589-019-0447-7. Epub 2020 Jan 13. Nat Chem Biol. 2020. PMID: 31932720 Free PMC article.

8

A memory of eS25 loss drives resistance phenotypes.

Johnson AG, Flynn RA, Lapointe CP, Ooi YS, Zhao ML, Richards CM, Qiao W, Yamada SB, Couthouis J, Gitler AD, Carette JE, Puglisi JD. Johnson AG, et al. Among authors: carette je. Nucleic Acids Res. 2020 Jul 27;48(13):7279-7297. doi: 10.1093/nar/gkaa444. Nucleic Acids Res. 2020. PMID: 32463448 Free PMC article.

9

Haploid genetic screens in human cells identify host factors used by pathogens.

Carette JE, Guimaraes CP, Varadarajan M, Park AS, Wuethrich I, Godarova A, Kotecki M, Cochran BH, Spooner E, Ploegh HL, Brummelkamp TR. Carette JE, et al. Science. 2009 Nov 27;326(5957):1231-5. doi: 10.1126/science.1178955. Science. 2009. PMID: 19965467

10

Generation of iPSCs from cultured human malignant cells.

Carette JE, Pruszak J, Varadarajan M, Blomen VA, Gokhale S, Camargo FD, Wernig M, Jaenisch R, Brummelkamp TR. Carette JE, et al. Blood. 2010 May 20;115(20):4039-42. doi: 10.1182/blood-2009-07-231845. Epub 2010 Mar 16. Blood. 2010. PMID: 20233975 Free PMC article.

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