Popplewell L - Search Results

1

Mutation-Directed Therapeutics for Neurofibromatosis Type I.

Leier A, Bedwell DM, Chen AT, Dickson G, Keeling KM, Kesterson RA, Korf BR, Marquez Lago TT, Müller UF, Popplewell L, Zhou J, Wallis D. Leier A, et al. Among authors: popplewell l. Mol Ther Nucleic Acids. 2020 Jun 5;20:739-753. doi: 10.1016/j.omtn.2020.04.012. Epub 2020 Apr 29. Mol Ther Nucleic Acids. 2020. PMID: 32408052 Free PMC article. Review.

2

Dystrophic phenotype induced in vitro by antibody blockade of muscle alpha-dystroglycan-laminin interaction.

Brown SC, Fassati A, Popplewell L, Page AM, Henry MD, Campbell KP, Dickson G. Brown SC, et al. Among authors: popplewell l. J Cell Sci. 1999 Jan;112 ( Pt 2):209-16. doi: 10.1242/jcs.112.2.209. J Cell Sci. 1999. PMID: 9858474

3

Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene.

Popplewell LJ, Trollet C, Dickson G, Graham IR. Popplewell LJ, et al. Mol Ther. 2009 Mar;17(3):554-61. doi: 10.1038/mt.2008.287. Epub 2009 Jan 13. Mol Ther. 2009. PMID: 19142179 Free PMC article.

4

Gene therapy for muscular dystrophy: current progress and future prospects.

Trollet C, Athanasopoulos T, Popplewell L, Malerba A, Dickson G. Trollet C, et al. Among authors: popplewell l. Expert Opin Biol Ther. 2009 Jul;9(7):849-66. doi: 10.1517/14712590903029164. Expert Opin Biol Ther. 2009. PMID: 19527108 Review.

5

Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials.

Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, Muntoni F, Graham IR, Dickson G. Popplewell LJ, et al. Neuromuscul Disord. 2010 Feb;20(2):102-10. doi: 10.1016/j.nmd.2009.10.013. Epub 2010 Jan 15. Neuromuscul Disord. 2010. PMID: 20079639

6

Antisense-induced myostatin exon skipping leads to muscle hypertrophy in mice following octa-guanidine morpholino oligomer treatment.

Kang JK, Malerba A, Popplewell L, Foster K, Dickson G. Kang JK, et al. Among authors: popplewell l. Mol Ther. 2011 Jan;19(1):159-64. doi: 10.1038/mt.2010.212. Epub 2010 Oct 5. Mol Ther. 2011. PMID: 20924365 Free PMC article.

7

Bioinformatic and functional optimization of antisense phosphorodiamidate morpholino oligomers (PMOs) for therapeutic modulation of RNA splicing in muscle.

Popplewell LJ, Graham IR, Malerba A, Dickson G. Popplewell LJ, et al. Methods Mol Biol. 2011;709:153-78. doi: 10.1007/978-1-61737-982-6_10. Methods Mol Biol. 2011. PMID: 21194027

8

Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice.

Koo T, Malerba A, Athanasopoulos T, Trollet C, Boldrin L, Ferry A, Popplewell L, Foster H, Foster K, Dickson G. Koo T, et al. Among authors: popplewell l. Hum Gene Ther. 2011 Nov;22(11):1379-88. doi: 10.1089/hum.2011.020. Epub 2011 May 25. Hum Gene Ther. 2011. PMID: 21453126 Free PMC article.

9

Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in Duchenne muscular dystrophy.

Popplewell LJ, Abu-Dayya A, Khanna T, Flinterman M, Abdul Khalique N, Raju L, Øpstad CL, Sliwka HR, Partali V, Dickson G, Pungente MD. Popplewell LJ, et al. Molecules. 2012 Jan 24;17(2):1138-48. doi: 10.3390/molecules17021138. Molecules. 2012. PMID: 22274137 Free PMC article.

10

Optimizing antisense oligonucleotides using phosphorodiamidate morpholino oligomers.

Popplewell LJ, Malerba A, Dickson G. Popplewell LJ, et al. Methods Mol Biol. 2012;867:143-67. doi: 10.1007/978-1-61779-767-5_10. Methods Mol Biol. 2012. PMID: 22454060

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