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Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.
Meakin PJ, Coull BM, Tuharska Z, McCaffery C, Akoumianakis I, Antoniades C, Brown J, Griffin KJ, Platt F, Ozber CH, Yuldasheva NY, Makava N, Skromna A, Prescott A, McNeilly AD, Siddiqui M, Palmer CN, Khan F, Ashford ML. Meakin PJ, et al. Among authors: mcneilly ad. J Clin Invest. 2020 Aug 3;130(8):4104-4117. doi: 10.1172/JCI122237. J Clin Invest. 2020. PMID: 32407295 Free PMC article.
Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.
Meakin PJ, Jalicy SM, Montagut G, Allsop DJP, Cavellini DL, Irvine SW, McGinley C, Liddell MK, McNeilly AD, Parmionova K, Liu YR, Bailey CLS, Dale JK, Heisler LK, McCrimmon RJ, Ashford MLJ. Meakin PJ, et al. Among authors: mcneilly ad. Sci Rep. 2018 Jan 8;8(1):55. doi: 10.1038/s41598-017-18388-6. Sci Rep. 2018. PMID: 29311632 Free PMC article.
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2).
Sharma RS, Harrison DJ, Kisielewski D, Cassidy DM, McNeilly AD, Gallagher JR, Walsh SV, Honda T, McCrimmon RJ, Dinkova-Kostova AT, Ashford MLJ, Dillon JF, Hayes JD. Sharma RS, et al. Among authors: mcneilly ad. Cell Mol Gastroenterol Hepatol. 2017 Dec 13;5(3):367-398. doi: 10.1016/j.jcmgh.2017.11.016. eCollection 2018 Mar. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29552625 Free PMC article.
44 results