Pessoa-Mahana CD - Search Results

1

Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.

Rodríguez-Lavado J, Gallardo-Garrido C, Mallea M, Bustos V, Osorio R, Hödar-Salazar M, Chung H, Araya-Maturana R, Lorca M, Pessoa-Mahana CD, Mella-Raipán J, Saitz C, Jaque P, Reyes-Parada M, Iturriaga-Vásquez P, Pessoa-Mahana H. Rodríguez-Lavado J, et al. Among authors: pessoa mahana cd. Eur J Med Chem. 2020 Jul 15;198:112368. doi: 10.1016/j.ejmech.2020.112368. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32388114

2

Biological evaluation of novel 6-Arylbenzimidazo[1,2-c]quinazoline derivatives as inhibitors of LPS-induced TNF-alpha secretion.

Galarce GD, Foncea RE, Edwards AM, Pessoa-Mahana H, Pessoa-Mahana CD, Ebensperger RA. Galarce GD, et al. Biol Res. 2008;41(1):43-50. Epub 2008 Aug 21. Biol Res. 2008. PMID: 18769762 Free article.

3

Antioxidant capacity of pure compounds and complex mixtures evaluated by the ORAC-pyrogallol red assay in the presence of Triton X-100 micelles.

Romero M, Rojano B, Mella-Raipán J, Pessoa-Mahana CD, Lissi E, López-Alarcón C. Romero M, et al. Molecules. 2010 Sep 1;15(9):6152-67. doi: 10.3390/molecules15096152. Molecules. 2010. PMID: 20877213 Free PMC article.

4

Evaluation of the membrane permeability (PAMPA and skin) of benzimidazoles with potential cannabinoid activity and their relation with the Biopharmaceutics Classification System (BCS).

Alvarez-Figueroa MJ, Pessoa-Mahana CD, Palavecino-González ME, Mella-Raipán J, Espinosa-Bustos C, Lagos-Muñoz ME. Alvarez-Figueroa MJ, et al. AAPS PharmSciTech. 2011 Jun;12(2):573-8. doi: 10.1208/s12249-011-9622-1. Epub 2011 May 4. AAPS PharmSciTech. 2011. PMID: 21538213 Free PMC article.

5

Synthesis, docking studies and biological evaluation of benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one derivatives on 5-HT1A serotonin receptors.

Pessoa-Mahana H, Recabarren-Gajardo G, Temer JF, Zapata-Torres G, Pessoa-Mahana CD, Barría CS, Araya-Maturana R. Pessoa-Mahana H, et al. Molecules. 2012 Feb 3;17(2):1388-407. doi: 10.3390/molecules17021388. Molecules. 2012. PMID: 22306829 Free PMC article.

6

Synthesis, 5-hydroxytryptamine1A receptor affinity and docking studies of 3-[3-(4-aryl-1-piperazinyl)-propyl]-1H-indole derivatives.

Pessoa-Mahana H, Núñez CU, Araya-Maturana R, Barría CS, Zapata-Torres G, Pessoa-Mahana CD, Iturriaga-Vasquez P, Mella-Raipán J, Reyes-Parada M, Celis-Barros C. Pessoa-Mahana H, et al. Chem Pharm Bull (Tokyo). 2012;60(5):632-8. doi: 10.1248/cpb.60.632. Chem Pharm Bull (Tokyo). 2012. PMID: 22689401 Free article.

7

Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles--a new family of high affinity CB1 cannabinoid ligands.

Mella-Raipán JA, Lagos CF, Recabarren-Gajardo G, Espinosa-Bustos C, Romero-Parra J, Pessoa-Mahana H, Iturriaga-Vásquez P, Pessoa-Mahana CD. Mella-Raipán JA, et al. Molecules. 2013 Apr 4;18(4):3972-4001. doi: 10.3390/molecules18043972. Molecules. 2013. PMID: 23558540 Free PMC article.

8

Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.

Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884

9

Synthesis and biological screening of novel indolalkyl arenes targeting the serotonine transporter.

Ojeda-Gómez C, Pessoa-Mahana H, Iturriaga-Vásquez P, Pessoa-Mahana CD, Recabarren-Gajardo G, Méndez-Rojas C. Ojeda-Gómez C, et al. Arch Pharm (Weinheim). 2014 Mar;347(3):174-84. doi: 10.1002/ardp.201300321. Epub 2013 Dec 11. Arch Pharm (Weinheim). 2014. PMID: 24339227

10

Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.

Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513

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