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The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network.
Beilina A, Bonet-Ponce L, Kumaran R, Kordich JJ, Ishida M, Mamais A, Kaganovich A, Saez-Atienzar S, Gershlick DC, Roosen DA, Pellegrini L, Malkov V, Fell MJ, Harvey K, Bonifacino JS, Moore DJ, Cookson MR. Beilina A, et al. Among authors: moore dj. Cell Rep. 2020 May 5;31(5):107614. doi: 10.1016/j.celrep.2020.107614. Cell Rep. 2020. PMID: 32375042 Free PMC article.
Mechanisms of LRRK2-mediated neurodegeneration.
Tsika E, Moore DJ. Tsika E, et al. Among authors: moore dj. Curr Neurol Neurosci Rep. 2012 Jun;12(3):251-60. doi: 10.1007/s11910-012-0265-8. Curr Neurol Neurosci Rep. 2012. PMID: 22441981 Free article. Review.
A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity.
Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, Yue Z, Bandopadhyay R, Glicksman MA, Moore DJ, Collins JJ, Wolozin B. Dusonchet J, et al. Among authors: moore dj. Hum Mol Genet. 2014 Sep 15;23(18):4887-905. doi: 10.1093/hmg/ddu202. Epub 2014 May 2. Hum Mol Genet. 2014. PMID: 24794857 Free PMC article.
Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration.
Tsika E, Kannan M, Foo CS, Dikeman D, Glauser L, Gellhaar S, Galter D, Knott GW, Dawson TM, Dawson VL, Moore DJ. Tsika E, et al. Among authors: moore dj. Neurobiol Dis. 2014 Nov;71:345-58. doi: 10.1016/j.nbd.2014.08.027. Epub 2014 Aug 29. Neurobiol Dis. 2014. PMID: 25174890 Free PMC article.
1,033 results