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A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Soda Y, Tani K, Bai Y, Saiki M, Chen M, Izawa K, Kobayashi S, Takahashi S, Uchimaru K, Kuwabara T, Warashina M, Tanabe T, Miyoshi H, Sugita K, Nakazawa S, Tojo A, Taira K, Asano S. Soda Y, et al. Among authors: kobayashi s. Blood. 2004 Jul 15;104(2):356-63. doi: 10.1182/blood-2003-06-1948. Epub 2004 Mar 23. Blood. 2004. PMID: 15039277 Free article.
CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome-positive acute lymphoblastic leukemia cells.
Harata M, Soda Y, Tani K, Ooi J, Takizawa T, Chen M, Bai Y, Izawa K, Kobayashi S, Tomonari A, Nagamura F, Takahashi S, Uchimaru K, Iseki T, Tsuji T, Takahashi TA, Sugita K, Nakazawa S, Tojo A, Maruyama K, Asano S. Harata M, et al. Among authors: kobayashi s. Blood. 2004 Sep 1;104(5):1442-9. doi: 10.1182/blood-2004-02-0588. Epub 2004 May 20. Blood. 2004. PMID: 15155467 Free article.
Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth.
Asanuma S, Yamagishi M, Kawanami K, Nakano K, Sato-Otsubo A, Muto S, Sanada M, Yamochi T, Kobayashi S, Utsunomiya A, Iwanaga M, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T. Asanuma S, et al. Among authors: kobayashi s. Cancer Sci. 2013 Aug;104(8):1097-106. doi: 10.1111/cas.12181. Epub 2013 May 19. Cancer Sci. 2013. PMID: 23600753 Free PMC article.
CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-I-infected cells in adult T-cell leukemia/lymphoma.
Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K. Kobayashi S, et al. Clin Cancer Res. 2014 Jun 1;20(11):2851-61. doi: 10.1158/1078-0432.CCR-13-3169. Epub 2014 Apr 11. Clin Cancer Res. 2014. PMID: 24727323
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