Kang DW - Search Results

1

A Preclinical Investigation into the Effects of Aging on Dermal Hyaluronan Properties and Reconstitution Following Recombinant Human Hyaluronidase PH20 Administration.

Connor RJ, Blouw B, Cowell J, Chen K, Zhao C, Kang DW. Connor RJ, et al. Among authors: kang dw. Dermatol Ther (Heidelb). 2020 Jun;10(3):503-513. doi: 10.1007/s13555-020-00380-0. Epub 2020 May 2. Dermatol Ther (Heidelb). 2020. PMID: 32361894 Free PMC article.

2

Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats.

Styles IK, Feeney OM, Nguyen TH, Brundel DHS, Kang DW, Clift R, McIntosh MP, Porter CJH. Styles IK, et al. Among authors: kang dw. J Control Release. 2019 Dec 10;315:85-96. doi: 10.1016/j.jconrel.2019.10.040. Epub 2019 Oct 23. J Control Release. 2019. PMID: 31655131

3

A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Hyaluronidase PH20 Administered Intravenously in Healthy Volunteers.

Printz MA, Dychter SS, DeNoia EP, Harrigan R, Sugarman BJ, Zepeda M, Souratha J, Kang DW, Maneval DC. Printz MA, et al. Among authors: kang dw. Curr Ther Res Clin Exp. 2020 Aug 19;93:100604. doi: 10.1016/j.curtheres.2020.100604. eCollection 2020. Curr Ther Res Clin Exp. 2020. PMID: 32963641 Free PMC article.

4

Use of computed tomography to assess subcutaneous drug dispersion with recombinant human hyaluronidase PH20 in a swine model.

Connor RJ, Taverna DM, Thrall K, LaBarre MJ, Kang DW. Connor RJ, et al. Among authors: kang dw. J Pharmacol Toxicol Methods. 2020 Nov-Dec;106:106936. doi: 10.1016/j.vascn.2020.106936. Epub 2020 Oct 22. J Pharmacol Toxicol Methods. 2020. PMID: 33191187 Free article.

5

Subcutaneous Injection Performance in Yucatan Miniature Pigs with and without Human Hyaluronidase and Auto-injector Tolerability in Humans.

Shi GH, Connor RJ, Collins DS, Kang DW. Shi GH, et al. Among authors: kang dw. AAPS PharmSciTech. 2021 Jan 6;22(1):39. doi: 10.1208/s12249-020-01880-0. AAPS PharmSciTech. 2021. PMID: 33409604 Free PMC article.

6

Dispersive effects and focused biodistribution of recombinant human hyaluronidase PH20: A locally acting and transiently active permeation enhancer.

Kang DW, Bittner B, Sugarman BJ, Zepeda ML, Printz MA. Kang DW, et al. PLoS One. 2021 Jul 22;16(7):e0254765. doi: 10.1371/journal.pone.0254765. eCollection 2021. PLoS One. 2021. PMID: 34292990 Free PMC article.

7

PEGylated recombinant human hyaluronidase (PEGPH20) pre-treatment improves intra-tumour distribution and efficacy of paclitaxel in preclinical models.

Morosi L, Meroni M, Ubezio P, Fuso Nerini I, Minoli L, Porcu L, Panini N, Colombo M, Blouw B, Kang DW, Davoli E, Zucchetti M, D'Incalci M, Frapolli R. Morosi L, et al. Among authors: kang dw. J Exp Clin Cancer Res. 2021 Sep 10;40(1):286. doi: 10.1186/s13046-021-02070-x. J Exp Clin Cancer Res. 2021. PMID: 34507591 Free PMC article.

8

Safety of recombinant human hyaluronidase PH20 for subcutaneous drug delivery.

Knowles SP, Printz MA, Kang DW, LaBarre MJ, Tannenbaum RP. Knowles SP, et al. Among authors: kang dw. Expert Opin Drug Deliv. 2021 Nov;18(11):1673-1685. doi: 10.1080/17425247.2021.1981286. Epub 2021 Sep 29. Expert Opin Drug Deliv. 2021. PMID: 34585991 Free article.

9

Risk Factors, Hyaluronidase Expression, and Clinical Immunogenicity of Recombinant Human Hyaluronidase PH20, an Enzyme Enabling Subcutaneous Drug Administration.

Printz MA, Sugarman BJ, Paladini RD, Jorge MC, Wang Y, Kang DW, Maneval DC, LaBarre MJ. Printz MA, et al. Among authors: kang dw. AAPS J. 2022 Oct 20;24(6):110. doi: 10.1208/s12248-022-00757-3. AAPS J. 2022. PMID: 36266598

10

Investigating the contribution of hyaluronan to the breast tumour microenvironment using multiparametric MRI and MR elastography.

Reeves EL, Li J, Zormpas-Petridis K, Boult JKR, Sullivan J, Cummings C, Blouw B, Kang D, Sinkus R, Bamber JC, Jamin Y, Robinson SP. Reeves EL, et al. Mol Oncol. 2023 Jun;17(6):1076-1092. doi: 10.1002/1878-0261.13437. Epub 2023 May 3. Mol Oncol. 2023. PMID: 37081807 Free PMC article.

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