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Blockade of CD73 delays glioblastoma growth by modulating the immune environment.
Azambuja JH, Schuh RS, Michels LR, Iser IC, Beckenkamp LR, Roliano GG, Lenz GS, Scholl JN, Sévigny J, Wink MR, Stefani MA, Battastini AMO, Figueiró F, Teixeira HF, Braganhol E. Azambuja JH, et al. Among authors: sevigny j. Cancer Immunol Immunother. 2020 Sep;69(9):1801-1812. doi: 10.1007/s00262-020-02569-w. Epub 2020 Apr 29. Cancer Immunol Immunother. 2020. PMID: 32350590 Free PMC article.
Overexpression of NTPDase2 in gliomas promotes systemic inflammation and pulmonary injury.
Braganhol E, Zanin RF, Bernardi A, Bergamin LS, Cappellari AR, Campesato LF, Morrone FB, Campos MM, Calixto JB, Edelweiss MI, Wink MR, Sévigny J, Robson SC, Battastini AM. Braganhol E, et al. Among authors: sevigny j. Purinergic Signal. 2012 Jun;8(2):235-43. doi: 10.1007/s11302-011-9276-1. Epub 2011 Oct 30. Purinergic Signal. 2012. PMID: 22038661 Free PMC article.
Homocysteine modifies extracellular ATP availability in macrophages.
Zanin RF, Bergamin LS, Braganhol E, Sévigny J, de Souza Wyse AT, Battastini AM. Zanin RF, et al. Among authors: sevigny j. Toxicol In Vitro. 2013 Dec;27(8):2273-8. doi: 10.1016/j.tiv.2013.09.001. Epub 2013 Sep 19. Toxicol In Vitro. 2013. PMID: 24055814
Nucleotide receptors control IL-8/CXCL8 and MCP-1/CCL2 secretions as well as proliferation in human glioma cells.
Braganhol E, Kukulski F, Lévesque SA, Fausther M, Lavoie EG, Zanotto-Filho A, Bergamin LS, Pelletier J, Bahrami F, Ben Yebdri F, Fonseca Moreira JC, Battastini AM, Sévigny J. Braganhol E, et al. Among authors: sevigny j. Biochim Biophys Acta. 2015 Jan;1852(1):120-30. doi: 10.1016/j.bbadis.2014.10.014. Epub 2014 Oct 30. Biochim Biophys Acta. 2015. PMID: 25445541 Free article.
Methotrexate up-regulates ecto-5'-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment.
Figueiró F, de Oliveira CP, Bergamin LS, Rockenbach L, Mendes FB, Jandrey EH, Moritz CE, Pettenuzzo LF, Sévigny J, Guterres SS, Pohlmann AR, Battastini AM. Figueiró F, et al. Among authors: sevigny j. Purinergic Signal. 2016 Jun;12(2):303-12. doi: 10.1007/s11302-016-9505-8. Epub 2016 Feb 24. Purinergic Signal. 2016. PMID: 26910734 Free PMC article.
366 results