Rutter GA - Search Results

1

The pore-forming subunit MCU of the mitochondrial Ca²⁺ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.

Georgiadou E, Haythorne E, Dickerson MT, Lopez-Noriega L, Pullen TJ, da Silva Xavier G, Davis SPX, Martinez-Sanchez A, Semplici F, Rizzuto R, McGinty JA, French PM, Cane MC, Jacobson DA, Leclerc I, Rutter GA. Georgiadou E, et al. Among authors: rutter ga. Diabetologia. 2020 Jul;63(7):1368-1381. doi: 10.1007/s00125-020-05148-x. Epub 2020 Apr 29. Diabetologia. 2020. PMID: 32350566 Free PMC article.

2

Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion.

Rutter GA, Theler JM, Murgia M, Wollheim CB, Pozzan T, Rizzuto R. Rutter GA, et al. J Biol Chem. 1993 Oct 25;268(30):22385-90. J Biol Chem. 1993. PMID: 8226749 Free article.

3

Integrating cytosolic calcium signals into mitochondrial metabolic responses.

Robb-Gaspers LD, Burnett P, Rutter GA, Denton RM, Rizzuto R, Thomas AP. Robb-Gaspers LD, et al. Among authors: rutter ga. EMBO J. 1998 Sep 1;17(17):4987-5000. doi: 10.1093/emboj/17.17.4987. EMBO J. 1998. PMID: 9724635 Free PMC article.

4

Calcium and organelles: a two-sided story.

Rutter GA, Fasolato C, Rizzuto R. Rutter GA, et al. Biochem Biophys Res Commun. 1998 Dec 30;253(3):549-57. doi: 10.1006/bbrc.1998.9727. Biochem Biophys Res Commun. 1998. PMID: 9918765 Review. No abstract available.

5

Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

Kennedy HJ, Pouli AE, Ainscow EK, Jouaville LS, Rizzuto R, Rutter GA. Kennedy HJ, et al. Among authors: rutter ga. J Biol Chem. 1999 May 7;274(19):13281-91. doi: 10.1074/jbc.274.19.13281. J Biol Chem. 1999. PMID: 10224088 Free article.

6

Present and potential future use of gene therapy for the treatment of non-insulin dependent diabetes mellitus (Review).

Freeman DJ, Leclerc I, Rutter GA. Freeman DJ, et al. Among authors: rutter ga. Int J Mol Med. 1999 Dec;4(6):585-92. doi: 10.3892/ijmm.4.6.585. Int J Mol Med. 1999. PMID: 10567666 Review.

7

Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming.

Jouaville LS, Pinton P, Bastianutto C, Rutter GA, Rizzuto R. Jouaville LS, et al. Among authors: rutter ga. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13807-12. doi: 10.1073/pnas.96.24.13807. Proc Natl Acad Sci U S A. 1999. PMID: 10570154 Free PMC article.

8

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression.

da Silva Xavier G, Leclerc I, Salt IP, Doiron B, Hardie DG, Kahn A, Rutter GA. da Silva Xavier G, et al. Among authors: rutter ga. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4023-8. doi: 10.1073/pnas.97.8.4023. Proc Natl Acad Sci U S A. 2000. PMID: 10760274 Free PMC article.

9

Regulation of mitochondrial metabolism by ER Ca2+ release: an intimate connection.

Rutter GA, Rizzuto R. Rutter GA, et al. Trends Biochem Sci. 2000 May;25(5):215-21. doi: 10.1016/s0968-0004(00)01585-1. Trends Biochem Sci. 2000. PMID: 10782088

10

Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2.

Rafiq I, da Silva Xavier G, Hooper S, Rutter GA. Rafiq I, et al. Among authors: rutter ga. J Biol Chem. 2000 May 26;275(21):15977-84. doi: 10.1074/jbc.275.21.15977. J Biol Chem. 2000. PMID: 10821851 Free article.

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