Jacobson DA - Search Results

1

The pore-forming subunit MCU of the mitochondrial Ca²⁺ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.

Georgiadou E, Haythorne E, Dickerson MT, Lopez-Noriega L, Pullen TJ, da Silva Xavier G, Davis SPX, Martinez-Sanchez A, Semplici F, Rizzuto R, McGinty JA, French PM, Cane MC, Jacobson DA, Leclerc I, Rutter GA. Georgiadou E, et al. Among authors: da silva xavier g, jacobson da. Diabetologia. 2020 Jul;63(7):1368-1381. doi: 10.1007/s00125-020-05148-x. Epub 2020 Apr 29. Diabetologia. 2020. PMID: 32350566 Free PMC article.

2

G6PC2: a negative regulator of basal glucose-stimulated insulin secretion.

Pound LD, Oeser JK, O'Brien TP, Wang Y, Faulman CJ, Dadi PK, Jacobson DA, Hutton JC, McGuinness OP, Shiota M, O'Brien RM. Pound LD, et al. Among authors: jacobson da. Diabetes. 2013 May;62(5):1547-56. doi: 10.2337/db12-1067. Epub 2012 Dec 28. Diabetes. 2013. PMID: 23274894 Free PMC article.

3

Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.

Baerenwald DA, Bonnefond A, Bouatia-Naji N, Flemming BP, Umunakwe OC, Oeser JK, Pound LD, Conley NL, Cauchi S, Lobbens S, Eury E, Balkau B, Lantieri O; MAGIC Investigators; Dadi PK, Jacobson DA, Froguel P, O'Brien RM. Baerenwald DA, et al. Among authors: jacobson da. Diabetologia. 2013 Jun;56(6):1306-16. doi: 10.1007/s00125-013-2875-3. Epub 2013 Mar 19. Diabetologia. 2013. PMID: 23508304 Free PMC article.

4

Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance.

Dadi PK, Vierra NC, Ustione A, Piston DW, Colbran RJ, Jacobson DA. Dadi PK, et al. Among authors: jacobson da. J Biol Chem. 2014 May 2;289(18):12435-45. doi: 10.1074/jbc.M114.562587. Epub 2014 Mar 13. J Biol Chem. 2014. PMID: 24627477 Free PMC article.

5

Pancreatic β-cell-specific ablation of TASK-1 channels augments glucose-stimulated calcium entry and insulin secretion, improving glucose tolerance.

Dadi PK, Vierra NC, Jacobson DA. Dadi PK, et al. Among authors: jacobson da. Endocrinology. 2014 Oct;155(10):3757-68. doi: 10.1210/en.2013-2051. Epub 2014 Jun 16. Endocrinology. 2014. PMID: 24932805 Free PMC article.

6

Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis.

Vierra NC, Dadi PK, Jeong I, Dickerson M, Powell DR, Jacobson DA. Vierra NC, et al. Among authors: jacobson da. Diabetes. 2015 Nov;64(11):3818-28. doi: 10.2337/db15-0280. Epub 2015 Aug 3. Diabetes. 2015. PMID: 26239056 Free PMC article.

7

Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion.

Golson ML, Dunn JC, Maulis MF, Dadi PK, Osipovich AB, Magnuson MA, Jacobson DA, Gannon M. Golson ML, et al. Among authors: jacobson da. Diabetes. 2015 Nov;64(11):3829-38. doi: 10.2337/db15-0465. Epub 2015 Aug 6. Diabetes. 2015. PMID: 26251404 Free PMC article.

8

Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.

Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F. Navarro G, et al. Among authors: jacobson da. Cell Metab. 2016 May 10;23(5):837-51. doi: 10.1016/j.cmet.2016.03.015. Epub 2016 Apr 28. Cell Metab. 2016. PMID: 27133133 Free PMC article.

9

Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx.

Dadi PK, Vierra NC, Days E, Dickerson MT, Vinson PN, Weaver CD, Jacobson DA. Dadi PK, et al. Among authors: jacobson da. ACS Chem Neurosci. 2017 Mar 15;8(3):558-568. doi: 10.1021/acschemneuro.6b00301. Epub 2016 Nov 23. ACS Chem Neurosci. 2017. PMID: 27805811 Free PMC article.

10

Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.

Dickerson MT, Vierra NC, Milian SC, Dadi PK, Jacobson DA. Dickerson MT, et al. Among authors: jacobson da. PLoS One. 2017 Apr 12;12(4):e0175069. doi: 10.1371/journal.pone.0175069. eCollection 2017. PLoS One. 2017. PMID: 28403169 Free PMC article.

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