Le HV - Search Results

1

Kappa opioid receptors internalization is protective against oxygen-glucose deprivation through β-arrestin activation and Akt-mediated signaling pathway.

Xu J, Chen F, Wang S, Akins NS, Hossain MI, Zhou Y, Huang J, Ji J, Xi J, Lin W, Grothusen J, Le HV, Liu R. Xu J, et al. Among authors: le hv. Neurochem Int. 2020 Jul;137:104748. doi: 10.1016/j.neuint.2020.104748. Epub 2020 Apr 24. Neurochem Int. 2020. PMID: 32339667 Free PMC article.

2

Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer.

Akins NS, Nielson TC, Le HV. Akins NS, et al. Among authors: le hv. Curr Top Med Chem. 2018;18(6):494-504. doi: 10.2174/1568026618666180523111351. Curr Top Med Chem. 2018. PMID: 29788892 Free PMC article. Review.

3

An efficient synthetic route to l-γ-methyleneglutamine and its amide derivatives, and their selective anticancer activity.

Hossain MI, Thomas AG, Mahdi F, Adam AT, Akins NS, Woodard MM, Paris JJ, Slusher BS, Le HV. Hossain MI, et al. Among authors: le hv. RSC Adv. 2021 Feb 24;11(13):7115-7128. doi: 10.1039/d0ra08249j. Epub 2021 Feb 10. RSC Adv. 2021. PMID: 33777357 Free PMC article.

4

Allopregnanolone and neuroHIV: Potential benefits of neuroendocrine modulation in the era of antiretroviral therapy.

Salahuddin MF, Qrareya AN, Mahdi F, Moss E, Akins NS, Li J, Le HV, Paris JJ. Salahuddin MF, et al. Among authors: le hv. J Neuroendocrinol. 2022 Feb;34(2):e13047. doi: 10.1111/jne.13047. Epub 2021 Oct 14. J Neuroendocrinol. 2022. PMID: 34651359 Free PMC article. Review.

5

6,5-Fused Ring, C2-Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects.

Akins NS, Mishra N, Harris HM, Dudhipala N, Kim SJ, Keasling AW, Majumdar S, Zjawiony JK, Paris JJ, Ashpole NM, Le HV. Akins NS, et al. Among authors: le hv. ChemMedChem. 2022 Apr 5;17(7):e202100684. doi: 10.1002/cmdc.202100684. Epub 2022 Feb 10. ChemMedChem. 2022. PMID: 35043597 Free PMC article.

6

Synthesis of 3,4,5-trisubstituted isoxazoles in water via a [3 + 2]-cycloaddition of nitrile oxides and 1,3-diketones, β-ketoesters, or β-ketoamides.

Hossain MI, Khan MIH, Kim SJ, Le HV. Hossain MI, et al. Among authors: le hv. Beilstein J Org Chem. 2022 Apr 22;18:446-458. doi: 10.3762/bjoc.18.47. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 35529890 Free PMC article.

7

Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders.

Cichon J, Liu R, Le HV. Cichon J, et al. Among authors: le hv. Transl Perioper Pain Med. 2022;9(2):452-457. Epub 2022 Jun 29. Transl Perioper Pain Med. 2022. PMID: 35959414 Free PMC article. No abstract available.

8

A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse.

Khan MIH, Sawyer BJ, Akins NS, Le HV. Khan MIH, et al. Among authors: le hv. Eur J Med Chem. 2022 Dec 5;243:114785. doi: 10.1016/j.ejmech.2022.114785. Epub 2022 Sep 22. Eur J Med Chem. 2022. PMID: 36179400 Review.

9

Synthesis and biological evaluation of tert-butyl ester and ethyl ester prodrugs of L-γ-methyleneglutamic acid amides for cancer.

Khan MIH, Mahdi F, Penfornis P, Akins NS, Hossain MI, Kim SJ, Sulochana SP, Adam AT, Tran TD, Tan C, Paolo Claudio P, Paris JJ, Le HV. Khan MIH, et al. Among authors: le hv. Bioorg Med Chem. 2023 Jan 15;78:117137. doi: 10.1016/j.bmc.2022.117137. Epub 2022 Dec 21. Bioorg Med Chem. 2023. PMID: 36603398 Free PMC article.

10

Alleviation of Cocaine Withdrawal and Pertinent Interactions between Salvinorin-Based Antagonists and Kappa Opioid Receptor.

Akins NS, Salahuddin MF, Pandey P, Kim SJ, Mahdi F, Khan MIH, Moss EM, Worth CJ, Keane MM, Chittiboyina AG, Doerksen RJ, Paris JJ, Le HV. Akins NS, et al. Among authors: le hv. ACS Chem Neurosci. 2023 Mar 1;14(5):958-976. doi: 10.1021/acschemneuro.2c00806. Epub 2023 Feb 16. ACS Chem Neurosci. 2023. PMID: 36795782

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