Biagioli M - Search Results

1

Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1.

Biagioli M, Carino A, Marchianò S, Roselli R, Di Giorgio C, Bordoni M, Fiorucci C, Sepe V, Conflitti P, Limongelli V, Distrutti E, Baldoni M, Zampella A, Fiorucci S. Biagioli M, et al. Biochem Pharmacol. 2020 Jul;177:113987. doi: 10.1016/j.bcp.2020.113987. Epub 2020 Apr 21. Biochem Pharmacol. 2020. PMID: 32330496

2

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.

Finamore C, Festa C, Renga B, Sepe V, Carino A, Masullo D, Biagioli M, Marchianò S, Capolupo A, Monti MC, Fiorucci S, Zampella A. Finamore C, et al. Among authors: biagioli m. Sci Rep. 2016 Jul 6;6:29320. doi: 10.1038/srep29320. Sci Rep. 2016. PMID: 27381677 Free PMC article.

3

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis.

Carino A, Cipriani S, Marchianò S, Biagioli M, Santorelli C, Donini A, Zampella A, Monti MC, Fiorucci S. Carino A, et al. Among authors: biagioli m. Sci Rep. 2017 Feb 16;7:42801. doi: 10.1038/srep42801. Sci Rep. 2017. PMID: 28202906 Free PMC article.

4

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.

Biagioli M, Carino A, Cipriani S, Francisci D, Marchianò S, Scarpelli P, Sorcini D, Zampella A, Fiorucci S. Biagioli M, et al. J Immunol. 2017 Jul 15;199(2):718-733. doi: 10.4049/jimmunol.1700183. Epub 2017 Jun 12. J Immunol. 2017. PMID: 28607110

5

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity.

Biagioli M, Laghi L, Carino A, Cipriani S, Distrutti E, Marchianò S, Parolin C, Scarpelli P, Vitali B, Fiorucci S. Biagioli M, et al. Front Pharmacol. 2017 Jul 28;8:505. doi: 10.3389/fphar.2017.00505. eCollection 2017. Front Pharmacol. 2017. PMID: 28804459 Free PMC article.

6

Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.

Carino A, Cipriani S, Marchianò S, Biagioli M, Scarpelli P, Zampella A, Monti MC, Fiorucci S. Carino A, et al. Among authors: biagioli m. Sci Rep. 2017 Oct 20;7(1):13689. doi: 10.1038/s41598-017-13102-y. Sci Rep. 2017. PMID: 29057935 Free PMC article.

7

Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases.

Biagioli M, Mencarelli A, Carino A, Cipriani S, Marchianò S, Fiorucci C, Donini A, Graziosi L, Baldelli F, Distrutti E, Costantino G, Fiorucci S. Biagioli M, et al. Inflamm Bowel Dis. 2017 Dec 19;24(1):123-135. doi: 10.1093/ibd/izx031. Inflamm Bowel Dis. 2017. PMID: 29272492

8

Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.

Carino A, Biagioli M, Marchianò S, Scarpelli P, Zampella A, Limongelli V, Fiorucci S. Carino A, et al. Among authors: biagioli m. Pharmacol Res. 2018 May;131:17-31. doi: 10.1016/j.phrs.2018.02.033. Epub 2018 Mar 9. Pharmacol Res. 2018. PMID: 29530598

9

Immunephenotype Predicts Response to Vedolizumab: Integrating Clinical and Biochemical Biomarkers in the Treatment of Inflammatory Bowel Diseases.

Fiorucci S, Biagioli M, Distrutti E. Fiorucci S, et al. Among authors: biagioli m. Dig Dis Sci. 2018 Sep;63(9):2168-2171. doi: 10.1007/s10620-018-5039-y. Dig Dis Sci. 2018. PMID: 29611077 No abstract available.

10

Future trends in the treatment of non-alcoholic steatohepatitis.

Fiorucci S, Biagioli M, Distrutti E. Fiorucci S, et al. Among authors: biagioli m. Pharmacol Res. 2018 Aug;134:289-298. doi: 10.1016/j.phrs.2018.07.014. Epub 2018 Jul 17. Pharmacol Res. 2018. PMID: 30021122 Review.

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