Andre R - Search Results

1

Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction.

Ghosh R, Wood-Kaczmar A, Dobson L, Smith EJ, Sirinathsinghji EC, Kriston-Vizi J, Hargreaves IP, Heaton R, Herrmann F, Abramov AY, Lam AJ, Heales SJ, Ketteler R, Bates GP, Andre R, Tabrizi SJ. Ghosh R, et al. Among authors: andre r. FASEB J. 2020 Jun;34(6):8139-8154. doi: 10.1096/fj.201902277RR. Epub 2020 Apr 23. FASEB J. 2020. PMID: 32329133 Free PMC article.

2

Disruption of immune cell function by mutant huntingtin in Huntington's disease pathogenesis.

Andre R, Carty L, Tabrizi SJ. Andre R, et al. Curr Opin Pharmacol. 2016 Feb;26:33-8. doi: 10.1016/j.coph.2015.09.008. Epub 2015 Oct 19. Curr Opin Pharmacol. 2016. PMID: 26461267 Review.

3

Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington's Disease T Lymphocytes.

Miller JR, Träger U, Andre R, Tabrizi SJ. Miller JR, et al. Among authors: andre r. PLoS One. 2015 Nov 3;10(11):e0141793. doi: 10.1371/journal.pone.0141793. eCollection 2015. PLoS One. 2015. PMID: 26529236 Free PMC article.

4

Misfolded PrP and a novel mechanism of proteasome inhibition.

Andre R, Tabrizi SJ. Andre R, et al. Prion. 2012 Jan-Mar;6(1):32-6. doi: 10.4161/pri.6.1.18272. Prion. 2012. PMID: 22453175 Free PMC article. Review.

5

HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.

Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ. Träger U, et al. Among authors: andre r. Brain. 2014 Mar;137(Pt 3):819-33. doi: 10.1093/brain/awt355. Epub 2014 Jan 22. Brain. 2014. PMID: 24459107 Free PMC article.

6

Biomarker development for Huntington's disease.

Andre R, Scahill RI, Haider S, Tabrizi SJ. Andre R, et al. Drug Discov Today. 2014 Jul;19(7):972-9. doi: 10.1016/j.drudis.2014.03.002. Epub 2014 Mar 12. Drug Discov Today. 2014. PMID: 24632006 Review.

7

Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells.

Miller JRC, Pfister EL, Liu W, Andre R, Träger U, Kennington LA, Lo K, Dijkstra S, Macdonald D, Ostroff G, Aronin N, Tabrizi SJ. Miller JRC, et al. Among authors: andre r. Sci Rep. 2017 Apr 24;7:46740. doi: 10.1038/srep46740. Sci Rep. 2017. PMID: 28436437 Free PMC article.

8

In vivo neutralization of the protagonist role of macrophages during the chronic inflammatory stage of Huntington's disease.

Pido-Lopez J, Andre R, Benjamin AC, Ali N, Farag S, Tabrizi SJ, Bates GP. Pido-Lopez J, et al. Among authors: andre r. Sci Rep. 2018 Jul 30;8(1):11447. doi: 10.1038/s41598-018-29792-x. Sci Rep. 2018. PMID: 30061661 Free PMC article.

9

FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.

Goold R, Flower M, Moss DH, Medway C, Wood-Kaczmar A, Andre R, Farshim P, Bates GP, Holmans P, Jones L, Tabrizi SJ. Goold R, et al. Among authors: andre r. Hum Mol Genet. 2019 Feb 15;28(4):650-661. doi: 10.1093/hmg/ddy375. Hum Mol Genet. 2019. PMID: 30358836 Free PMC article.

10

Inhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington's disease by etanercept treatment.

Pido-Lopez J, Tanudjojo B, Farag S, Bondulich MK, Andre R, Tabrizi SJ, Bates GP. Pido-Lopez J, et al. Among authors: andre r. Sci Rep. 2019 May 10;9(1):7202. doi: 10.1038/s41598-019-43627-3. Sci Rep. 2019. PMID: 31076648 Free PMC article.

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