Raj A - Search Results

1

Gene Networks with Transcriptional Bursting Recapitulate Rare Transient Coordinated High Expression States in Cancer.

Schuh L, Saint-Antoine M, Sanford EM, Emert BL, Singh A, Marr C, Raj A, Goyal Y. Schuh L, et al. Among authors: raj a. Cell Syst. 2020 Apr 22;10(4):363-378.e12. doi: 10.1016/j.cels.2020.03.004. Cell Syst. 2020. PMID: 32325034 Free PMC article.

2

Using variability in gene expression as a tool for studying gene regulation.

Padovan-Merhar O, Raj A. Padovan-Merhar O, et al. Among authors: raj a. Wiley Interdiscip Rev Syst Biol Med. 2013 Nov-Dec;5(6):751-9. doi: 10.1002/wsbm.1243. Epub 2013 Aug 29. Wiley Interdiscip Rev Syst Biol Med. 2013. PMID: 23996796 Free PMC article. Review.

3

Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms.

Padovan-Merhar O, Nair GP, Biaesch AG, Mayer A, Scarfone S, Foley SW, Wu AR, Churchman LS, Singh A, Raj A. Padovan-Merhar O, et al. Among authors: raj a. Mol Cell. 2015 Apr 16;58(2):339-52. doi: 10.1016/j.molcel.2015.03.005. Epub 2015 Apr 9. Mol Cell. 2015. PMID: 25866248 Free PMC article.

4

Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping.

Bartman CR, Hsu SC, Hsiung CC, Raj A, Blobel GA. Bartman CR, et al. Among authors: raj a. Mol Cell. 2016 Apr 21;62(2):237-247. doi: 10.1016/j.molcel.2016.03.007. Epub 2016 Apr 7. Mol Cell. 2016. PMID: 27067601 Free PMC article.

5

Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels.

Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS. Dar RD, et al. Among authors: raj a. PLoS One. 2016 Jul 28;11(7):e0158298. doi: 10.1371/journal.pone.0158298. eCollection 2016. PLoS One. 2016. PMID: 27467384 Free PMC article.

6

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.

Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A. Shaffer SM, et al. Among authors: raj a. Nature. 2017 Jun 15;546(7658):431-435. doi: 10.1038/nature22794. Epub 2017 Jun 7. Nature. 2017. PMID: 28607484 Free PMC article.

7

Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH.

Torre E, Dueck H, Shaffer S, Gospocic J, Gupte R, Bonasio R, Kim J, Murray J, Raj A. Torre E, et al. Among authors: raj a. Cell Syst. 2018 Feb 28;6(2):171-179.e5. doi: 10.1016/j.cels.2018.01.014. Epub 2018 Feb 14. Cell Syst. 2018. PMID: 29454938 Free PMC article.

8

Corrigendum: Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.

Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A. Shaffer SM, et al. Among authors: raj a. Nature. 2018 Mar 8;555(7695):274. doi: 10.1038/nature25162. Epub 2018 Feb 21. Nature. 2018. PMID: 29466340

9

ClampFISH detects individual nucleic acid molecules using click chemistry-based amplification.

Rouhanifard SH, Mellis IA, Dunagin M, Bayatpour S, Jiang CL, Dardani I, Symmons O, Emert B, Torre E, Cote A, Sullivan A, Stamatoyannopoulos JA, Raj A. Rouhanifard SH, et al. Among authors: raj a. Nat Biotechnol. 2018 Nov 12:10.1038/nbt.4286. doi: 10.1038/nbt.4286. Online ahead of print. Nat Biotechnol. 2018. PMID: 30418432 Free PMC article.

10

Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors.

Shaffer SM, Emert BL, Reyes Hueros RA, Cote C, Harmange G, Schaff DL, Sizemore AE, Gupte R, Torre E, Singh A, Bassett DS, Raj A. Shaffer SM, et al. Among authors: raj a. Cell. 2020 Aug 20;182(4):947-959.e17. doi: 10.1016/j.cell.2020.07.003. Epub 2020 Jul 30. Cell. 2020. PMID: 32735851 Free PMC article.

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