Patel CH - Search Results

1

Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells.

Oh MH, Sun IH, Zhao L, Leone RD, Sun IM, Xu W, Collins SL, Tam AJ, Blosser RL, Patel CH, Englert JM, Arwood ML, Wen J, Chan-Li Y, Tenora L, Majer P, Rais R, Slusher BS, Horton MR, Powell JD. Oh MH, et al. Among authors: patel ch. J Clin Invest. 2020 Jul 1;130(7):3865-3884. doi: 10.1172/JCI131859. J Clin Invest. 2020. PMID: 32324593 Free PMC article.

2

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.

Heikamp EB, Patel CH, Collins S, Waickman A, Oh MH, Sun IH, Illei P, Sharma A, Naray-Fejes-Toth A, Fejes-Toth G, Misra-Sen J, Horton MR, Powell JD. Heikamp EB, et al. Among authors: patel ch. Nat Immunol. 2014 May;15(5):457-64. doi: 10.1038/ni.2867. Epub 2014 Apr 6. Nat Immunol. 2014. PMID: 24705297 Free PMC article.

3

Cytosolic branched chain aminotransferase (BCATc) regulates mTORC1 signaling and glycolytic metabolism in CD4+ T cells.

Ananieva EA, Patel CH, Drake CH, Powell JD, Hutson SM. Ananieva EA, et al. Among authors: patel ch. J Biol Chem. 2014 Jul 4;289(27):18793-804. doi: 10.1074/jbc.M114.554113. Epub 2014 May 20. J Biol Chem. 2014. PMID: 24847056 Free PMC article.

4

Cellular size as a means of tracking mTOR activity and cell fate of CD4+ T cells upon antigen recognition.

Pollizzi KN, Waickman AT, Patel CH, Sun IH, Powell JD. Pollizzi KN, et al. Among authors: patel ch. PLoS One. 2015 Apr 7;10(4):e0121710. doi: 10.1371/journal.pone.0121710. eCollection 2015. PLoS One. 2015. PMID: 25849206 Free PMC article.

5

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.

Pollizzi KN, Patel CH, Sun IH, Oh MH, Waickman AT, Wen J, Delgoffe GM, Powell JD. Pollizzi KN, et al. Among authors: patel ch. J Clin Invest. 2015 May;125(5):2090-108. doi: 10.1172/JCI77746. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893604 Free PMC article.

6

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.

Pollizzi KN, Sun IH, Patel CH, Lo YC, Oh MH, Waickman AT, Tam AJ, Blosser RL, Wen J, Delgoffe GM, Powell JD. Pollizzi KN, et al. Among authors: patel ch. Nat Immunol. 2016 Jun;17(6):704-11. doi: 10.1038/ni.3438. Epub 2016 Apr 11. Nat Immunol. 2016. PMID: 27064374 Free PMC article.

7

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells.

Sadtler K, Estrellas K, Allen BW, Wolf MT, Fan H, Tam AJ, Patel CH, Luber BS, Wang H, Wagner KR, Powell JD, Housseau F, Pardoll DM, Elisseeff JH. Sadtler K, et al. Among authors: patel ch. Science. 2016 Apr 15;352(6283):366-70. doi: 10.1126/science.aad9272. Science. 2016. PMID: 27081073 Free PMC article.

8

Warburg meets epigenetics.

Patel CH, Powell JD. Patel CH, et al. Science. 2016 Oct 28;354(6311):419-420. doi: 10.1126/science.aak9776. Science. 2016. PMID: 27789830 No abstract available.

9

Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease.

Patel CH, Powell JD. Patel CH, et al. Curr Opin Immunol. 2017 Jun;46:82-88. doi: 10.1016/j.coi.2017.04.006. Epub 2017 May 15. Curr Opin Immunol. 2017. PMID: 28521236 Free PMC article. Review.

10

mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages.

Oh MH, Collins SL, Sun IH, Tam AJ, Patel CH, Arwood ML, Chan-Li Y, Powell JD, Horton MR. Oh MH, et al. Among authors: patel ch. Cell Rep. 2017 Sep 5;20(10):2439-2454. doi: 10.1016/j.celrep.2017.08.046. Cell Rep. 2017. PMID: 28877476 Free PMC article.

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