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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: zhang b, zhang lk. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: zhang l, zhang b. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z. Gao Y, et al. Among authors: zhang l, zhang b, zhang y. Science. 2020 May 15;368(6492):779-782. doi: 10.1126/science.abb7498. Epub 2020 Apr 10. Science. 2020. PMID: 32277040 Free PMC article.
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z. Zhang L, et al. Among authors: zhang b, zhang q, zhang x. Science. 2020 Jun 12;368(6496):1211-1219. doi: 10.1126/science.aba9102. Epub 2020 Apr 23. Science. 2020. PMID: 32327601
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