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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: jiang xm, jiang h. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Simulating the interactions of toxins with K+ channels.
Huang X, Liu H, Cui M, Fu W, Yu K, Chen K, Luo X, Shen J, Jiang H. Huang X, et al. Among authors: jiang h. Curr Pharm Des. 2004;10(9):1057-67. doi: 10.2174/1381612043452776. Curr Pharm Des. 2004. PMID: 15078133 Review.
Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A.
Luo C, Luo H, Zheng S, Gui C, Yue L, Yu C, Sun T, He P, Chen J, Shen J, Luo X, Li Y, Liu H, Bai D, Shen J, Yang Y, Li F, Zuo J, Hilgenfeld R, Pei G, Chen K, Shen X, Jiang H. Luo C, et al. Among authors: jiang h. Biochem Biophys Res Commun. 2004 Aug 27;321(3):557-65. doi: 10.1016/j.bbrc.2004.07.003. Biochem Biophys Res Commun. 2004. PMID: 15358143 Free PMC article.
Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations.
Chen S, Chen L, Tan J, Chen J, Du L, Sun T, Shen J, Chen K, Jiang H, Shen X. Chen S, et al. Among authors: jiang h. J Biol Chem. 2005 Jan 7;280(1):164-73. doi: 10.1074/jbc.M408211200. Epub 2004 Oct 26. J Biol Chem. 2005. PMID: 15507456 Free PMC article.
29,168 results
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