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Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation.
Mijnheer G, Lutter L, Mokry M, van der Wal M, Scholman R, Fleskens V, Pandit A, Tao W, Wekking M, Vervoort S, Roberts C, Petrelli A, Peeters JGC, Knijff M, de Roock S, Vastert S, Taams LS, van Loosdregt J, van Wijk F. Mijnheer G, et al. Among authors: fleskens v. Nat Commun. 2021 May 11;12(1):2710. doi: 10.1038/s41467-021-22975-7. Nat Commun. 2021. PMID: 33976194 Free PMC article.
Rapid temporal control of Foxp3 protein degradation by sirtuin-1.
van Loosdregt J, Brunen D, Fleskens V, Pals CE, Lam EW, Coffer PJ. van Loosdregt J, et al. Among authors: fleskens v. PLoS One. 2011 Apr 20;6(4):e19047. doi: 10.1371/journal.pone.0019047. PLoS One. 2011. PMID: 21533107 Free PMC article.
Canonical Wnt signaling negatively modulates regulatory T cell function.
van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ. van Loosdregt J, et al. Among authors: fleskens v. Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15. Immunity. 2013. PMID: 23954131 Free article.
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.
van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, Pan F, Zaiss DM, Coffer PJ. van Loosdregt J, et al. Among authors: fleskens v. Immunity. 2013 Aug 22;39(2):259-71. doi: 10.1016/j.immuni.2013.05.018. Immunity. 2013. PMID: 23973222 Free PMC article.
15 results