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Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation.
Hiromi T, Yokoyama U, Kurotaki D, Mamun A, Ishiwata R, Ichikawa Y, Nishihara H, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Takeuchi I, Masuda M, Breyer RM, Tamura T, Ishikawa Y. Hiromi T, et al. Among authors: ishikawa y. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):1559-1573. doi: 10.1161/ATVBAHA.120.314297. Epub 2020 Apr 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 32321307 Free PMC article.
Inhibition of EP4 signaling attenuates aortic aneurysm formation.
Yokoyama U, Ishiwata R, Jin MH, Kato Y, Suzuki O, Jin H, Ichikawa Y, Kumagaya S, Katayama Y, Fujita T, Okumura S, Sato M, Sugimoto Y, Aoki H, Suzuki S, Masuda M, Minamisawa S, Ishikawa Y. Yokoyama U, et al. Among authors: ishikawa y. PLoS One. 2012;7(5):e36724. doi: 10.1371/journal.pone.0036724. Epub 2012 May 3. PLoS One. 2012. PMID: 22570740 Free PMC article.
The prostanoid EP4 receptor and its signaling pathway.
Yokoyama U, Iwatsubo K, Umemura M, Fujita T, Ishikawa Y. Yokoyama U, et al. Among authors: ishikawa y. Pharmacol Rev. 2013 Jun 17;65(3):1010-52. doi: 10.1124/pr.112.007195. Print 2013 Jul. Pharmacol Rev. 2013. PMID: 23776144 Review.
Proteomic analysis of aortic smooth muscle cell secretions reveals an association of myosin heavy chain 11 with abdominal aortic aneurysm.
Yokoyama U, Arakawa N, Ishiwata R, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Matsumoto M, Koizumi N, Taguri M, Hirano H, Yoshimura K, Ogino H, Masuda M, Ishikawa Y. Yokoyama U, et al. Among authors: ishikawa y. Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H1012-H1018. doi: 10.1152/ajpheart.00329.2018. Epub 2018 Jul 13. Am J Physiol Heart Circ Physiol. 2018. PMID: 30004237 Free article.
Fibulin-1 Integrates Subendothelial Extracellular Matrices and Contributes to Anatomical Closure of the Ductus Arteriosus.
Ito S, Yokoyama U, Nakakoji T, Cooley MA, Sasaki T, Hatano S, Kato Y, Saito J, Nicho N, Iwasaki S, Umemura M, Fujita T, Masuda M, Asou T, Ishikawa Y. Ito S, et al. Among authors: ishikawa y. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2212-2226. doi: 10.1161/ATVBAHA.120.314729. Epub 2020 Jul 9. Arterioscler Thromb Vasc Biol. 2020. PMID: 32640908 Free PMC article.
3,770 results