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Correlation Analysis of Protein Expression of 10 HDAC/Sirtuin Isoenzymes with Sensitivities of 23 Anticancer Drugs in 17 Cancer Cell Lines and Potentiation of Drug Activity by Co-Treatment with HDAC Inhibitors.
Behnisch-Cornwell S, Grathwol CW, Schulig L, Voigt A, Baecker D, Link A, Bednarski PJ. Behnisch-Cornwell S, et al. Among authors: grathwol cw. Cancers (Basel). 2021 Dec 31;14(1):187. doi: 10.3390/cancers14010187. Cancers (Basel). 2021. PMID: 35008351 Free PMC article.
Crystal structure of benzo[h]quinoline-3-carbox-amide.
Grathwol CW, Chrysochos N, Elvers BJ, Link A, Schulzke C. Grathwol CW, et al. Acta Crystallogr E Crystallogr Commun. 2019 Nov 5;75(Pt 12):1828-1832. doi: 10.1107/S2056989019014440. eCollection 2019 Dec 1. Acta Crystallogr E Crystallogr Commun. 2019. PMID: 31871739 Free PMC article.
Engineering Regioselectivity of a P450 Monooxygenase Enables the Synthesis of Ursodeoxycholic Acid via 7β-Hydroxylation of Lithocholic Acid.
Grobe S, Badenhorst CPS, Bayer T, Hamnevik E, Wu S, Grathwol CW, Link A, Koban S, Brundiek H, Großjohann B, Bornscheuer UT. Grobe S, et al. Among authors: grathwol cw. Angew Chem Int Ed Engl. 2021 Jan 11;60(2):753-757. doi: 10.1002/anie.202012675. Epub 2020 Nov 12. Angew Chem Int Ed Engl. 2021. PMID: 33085147 Free PMC article.
Simultaneous quantification of acidic and basic flupirtine metabolites by supercritical fluid chromatography according to European Medicines Agency validation.
Hofstetter RK, Hasan M, Fassauer GM, Bock C, Surur AS, Behnisch S, Grathwol CW, Potlitz F, Oergel T, Siegmund W, Link A. Hofstetter RK, et al. Among authors: grathwol cw. J Chromatogr A. 2019 Oct 11;1603:338-347. doi: 10.1016/j.chroma.2019.04.067. Epub 2019 Apr 25. J Chromatogr A. 2019. PMID: 31056272 Clinical Trial.
Practical synthesis and biological screening of sulfonyl hydrazides.
Macara J, Caldeira C, Cunha J, Coelho JAS, Silva MJSA, Krämer K, Grathwol CW, Bräse S, Marques MMB. Macara J, et al. Among authors: grathwol cw. Org Biomol Chem. 2023 Mar 8;21(10):2118-2126. doi: 10.1039/d2ob02160a. Org Biomol Chem. 2023. PMID: 36606485