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14 results

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Page 1
Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy.
D'Amico G, Korhonen EA, Anisimov A, Zarkada G, Holopainen T, Hägerling R, Kiefer F, Eklund L, Sormunen R, Elamaa H, Brekken RA, Adams RH, Koh GY, Saharinen P, Alitalo K. D'Amico G, et al. Among authors: korhonen ea. J Clin Invest. 2014 Feb;124(2):824-34. doi: 10.1172/JCI68897. Epub 2014 Jan 16. J Clin Invest. 2014. PMID: 24430181 Free PMC article.
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.
Kim M, Allen B, Korhonen EA, Nitschké M, Yang HW, Baluk P, Saharinen P, Alitalo K, Daly C, Thurston G, McDonald DM. Kim M, et al. Among authors: korhonen ea. J Clin Invest. 2016 Sep 1;126(9):3511-25. doi: 10.1172/JCI84871. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548529 Free PMC article.
Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Korhonen EA, Lampinen A, Giri H, Anisimov A, Kim M, Allen B, Fang S, D'Amico G, Sipilä TJ, Lohela M, Strandin T, Vaheri A, Ylä-Herttuala S, Koh GY, McDonald DM, Alitalo K, Saharinen P. Korhonen EA, et al. J Clin Invest. 2016 Sep 1;126(9):3495-510. doi: 10.1172/JCI84923. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548530 Free PMC article.
High baseline Tie1 level predicts poor survival in metastatic breast cancer.
Tiainen L, Korhonen EA, Leppänen VM, Luukkaala T, Hämäläinen M, Tanner M, Lahdenperä O, Vihinen P, Jukkola A, Karihtala P, Aho S, Moilanen E, Alitalo K, Kellokumpu-Lehtinen PL. Tiainen L, et al. Among authors: korhonen ea. BMC Cancer. 2019 Jul 24;19(1):732. doi: 10.1186/s12885-019-5959-8. BMC Cancer. 2019. PMID: 31340773 Free PMC article. Clinical Trial.
Characterization of ANGPT2 mutations associated with primary lymphedema.
Leppänen VM, Brouillard P, Korhonen EA, Sipilä T, Jha SK, Revencu N, Labarque V, Fastré E, Schlögel M, Ravoet M, Singer A, Luzzatto C, Angelone D, Crichiutti G, D'Elia A, Kuurne J, Elamaa H, Koh GY, Saharinen P, Vikkula M, Alitalo K. Leppänen VM, et al. Among authors: korhonen ea. Sci Transl Med. 2020 Sep 9;12(560):eaax8013. doi: 10.1126/scitranslmed.aax8013. Sci Transl Med. 2020. PMID: 32908006
14 results