Ilaš J - Search Results

1

Efficient Synthesis of Hydroxy-Substituted 2-Aminobenzo[d]thiazole-6-carboxylic Acid Derivatives as New Building Blocks in Drug Discovery.

Durcik M, Toplak Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Mašič LP, Tomašič T. Durcik M, et al. Among authors: ilas j. ACS Omega. 2020 Mar 31;5(14):8305-8311. doi: 10.1021/acsomega.0c00768. eCollection 2020 Apr 14. ACS Omega. 2020. PMID: 32309742 Free PMC article.

2

Novel thrombin inhibitors incorporating weakly basic heterobicyclic P1-arginine mimetics: optimization via modification of P1 and P3 moieties.

Kranjc A, Peterlin-Masic L, Ilas J, Prezelj A, Stegnar M, Kikelj D. Kranjc A, et al. Among authors: ilas j. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3251-6. doi: 10.1016/j.bmcl.2004.03.085. Bioorg Med Chem Lett. 2004. PMID: 15149685

3

Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities.

Stefanic Anderluh P, Anderluh M, Ilas J, Mravljak J, Sollner Dolenc M, Stegnar M, Kikelj D. Stefanic Anderluh P, et al. Among authors: ilas j. J Med Chem. 2005 May 5;48(9):3110-3. doi: 10.1021/jm048984g. J Med Chem. 2005. PMID: 15857114

4

Peptides and pseudopeptides incorporating D-Phe-Pro-Arg and Arg-Gly-Asp lead sequences as potential antithrombotic agents.

Ilas J, Hudecz F, Süli-Vargha H, Kikelj D. Ilas J, et al. J Pept Sci. 2008 Aug;14(8):946-53. doi: 10.1002/psc.1030. J Pept Sci. 2008. PMID: 18383437

5

Novel potent and selective thrombin inhibitors based on a central 1,4-benzoxazin-3(4H)-one scaffold.

Ilas J, Tomasić T, Kikelj D. Ilas J, et al. J Med Chem. 2008 May 8;51(9):2863-7. doi: 10.1021/jm701622y. Epub 2008 Apr 16. J Med Chem. 2008. PMID: 18412326

6

3,4-Dihydro-2H-1,4-benzoxazine derivatives combining thrombin inhibitory and glycoprotein IIb/IIIa receptor antagonistic activity as a novel class of antithrombotic compounds with dual function.

Ilas J, Jakopin Z, Borstnar T, Stegnar M, Kikelj D. Ilas J, et al. J Med Chem. 2008 Sep 25;51(18):5617-29. doi: 10.1021/jm8003448. Epub 2008 Aug 27. J Med Chem. 2008. PMID: 18729445

7

Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities.

Ilić M, Kontogiorgis C, Hadjipavlou-Litina D, Ilaš J, Kikelj D. Ilić M, et al. Among authors: ilas j. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4705-9. doi: 10.1016/j.bmcl.2011.06.089. Epub 2011 Jun 25. Bioorg Med Chem Lett. 2011. PMID: 21757348

8

Multitarget antithrombotic drugs.

Ilić M, Kikelj D, Ilaš J. Ilić M, et al. Among authors: ilas j. Curr Top Med Chem. 2011 Nov;11(22):2834-48. doi: 10.2174/156802611798184364. Curr Top Med Chem. 2011. PMID: 22039882 Review.

9

Fluorinated dual antithrombotic compounds based on 1,4-benzoxazine scaffold.

Ilić M, Kikelj D, Ilaš J. Ilić M, et al. Among authors: ilas j. Eur J Med Chem. 2012 Apr;50:255-63. doi: 10.1016/j.ejmech.2012.01.059. Epub 2012 Feb 8. Eur J Med Chem. 2012. PMID: 22365562

10

Novel 1,4-benzoxazine and 1,4-benzodioxine inhibitors of angiogenesis.

Ilić M, Ilaš J, Dunkel P, Mátyus P, Boháč A, Liekens S, Kikelj D. Ilić M, et al. Among authors: ilas j. Eur J Med Chem. 2012 Dec;58:160-70. doi: 10.1016/j.ejmech.2012.10.001. Epub 2012 Oct 8. Eur J Med Chem. 2012. PMID: 23124213

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