Hoppe HC - Search Results

1

The in Vitro Antiplasmodial and Antiproliferative Activity of New Ferrocene-Based α-Aminocresols Targeting Hemozoin Inhibition and DNA Interaction.

Mbaba M, Dingle LMK, Swart T, Cash D, Laming D, de la Mare JA, Taylor D, Hoppe HC, Biot C, Edkins AL, Khanye SD. Mbaba M, et al. Among authors: hoppe hc. Chembiochem. 2020 Sep 14;21(18):2643-2658. doi: 10.1002/cbic.202000132. Epub 2020 May 27. Chembiochem. 2020. PMID: 32307798

2

Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction.

Feng TS, Guantai EM, Nell MJ, van Rensburg CE, Hoppe HC, Chibale K. Feng TS, et al. Among authors: hoppe hc. Bioorg Med Chem Lett. 2011 May 15;21(10):2882-6. doi: 10.1016/j.bmcl.2011.03.090. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21489789

3

Insights into the role of heme in the mechanism of action of antimalarials.

Combrinck JM, Mabotha TE, Ncokazi KK, Ambele MA, Taylor D, Smith PJ, Hoppe HC, Egan TJ. Combrinck JM, et al. Among authors: hoppe hc. ACS Chem Biol. 2013 Jan 18;8(1):133-7. doi: 10.1021/cb300454t. Epub 2012 Oct 11. ACS Chem Biol. 2013. PMID: 23043646 Free PMC article.

4

Dynamic Mitochondrial Localisation of STAT3 in the Cellular Adipogenesis Model 3T3-L1.

Kramer AH, Edkins AL, Hoppe HC, Prinsloo E. Kramer AH, et al. Among authors: hoppe hc. J Cell Biochem. 2015 Jul;116(7):1232-40. doi: 10.1002/jcb.25076. J Cell Biochem. 2015. PMID: 25565605

5

Indolyl-3-ethanone-α-thioethers: A promising new class of non-toxic antimalarial agents.

Svogie AL, Isaacs M, Hoppe HC, Khanye SD, Veale CG. Svogie AL, et al. Among authors: hoppe hc. Eur J Med Chem. 2016 May 23;114:79-88. doi: 10.1016/j.ejmech.2016.02.056. Epub 2016 Mar 3. Eur J Med Chem. 2016. PMID: 26974377

6

Synthesis and evaluation of substituted 4-(N-benzylamino)cinnamate esters as potential anti-cancer agents and HIV-1 integrase inhibitors.

Faridoon, Edkins AL, Isaacs M, Mnkandhla D, Hoppe HC, Kaye PT. Faridoon, et al. Among authors: hoppe hc. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3810-2. doi: 10.1016/j.bmcl.2016.05.023. Epub 2016 May 9. Bioorg Med Chem Lett. 2016. PMID: 27317645

7

Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates.

Lourens AC, Gravestock D, van Zyl RL, Hoppe HC, Kolesnikova N, Taweechai S, Yuthavong Y, Kamchonwongpaisan S, Rousseau AL. Lourens AC, et al. Among authors: hoppe hc. Org Biomol Chem. 2016 Aug 16;14(33):7899-911. doi: 10.1039/c6ob01350c. Org Biomol Chem. 2016. PMID: 27477595

8

Ferrocenyl and organic novobiocin derivatives: Synthesis and their in vitro biological activity.

Mbaba M, Mabhula AN, Boel N, Edkins AL, Isaacs M, Hoppe HC, Khanye SD. Mbaba M, et al. Among authors: hoppe hc. J Inorg Biochem. 2017 Jul;172:88-93. doi: 10.1016/j.jinorgbio.2017.04.014. Epub 2017 Apr 13. J Inorg Biochem. 2017. PMID: 28441548

9

Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors.

Sekgota KC, Majumder S, Isaacs M, Mnkandhla D, Hoppe HC, Khanye SD, Kriel FH, Coates J, Kaye PT. Sekgota KC, et al. Among authors: hoppe hc. Bioorg Chem. 2017 Dec;75:310-316. doi: 10.1016/j.bioorg.2017.09.015. Epub 2017 Sep 22. Bioorg Chem. 2017. PMID: 29080495

10

Expanding the SAR of Nontoxic Antiplasmodial Indolyl-3-ethanone Ethers and Thioethers.

Lunga MJ, Chisango RL, Weyers C, Isaacs M, Taylor D, Edkins AL, Khanye SD, Hoppe HC, Veale CGL. Lunga MJ, et al. Among authors: hoppe hc. ChemMedChem. 2018 Jul 6;13(13):1353-1362. doi: 10.1002/cmdc.201800235. Epub 2018 Jun 7. ChemMedChem. 2018. PMID: 29756273

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