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Page 1
β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance.
Novakovic B, Habibi E, Wang SY, Arts RJW, Davar R, Megchelenbrink W, Kim B, Kuznetsova T, Kox M, Zwaag J, Matarese F, van Heeringen SJ, Janssen-Megens EM, Sharifi N, Wang C, Keramati F, Schoonenberg V, Flicek P, Clarke L, Pickkers P, Heath S, Gut I, Netea MG, Martens JHA, Logie C, Stunnenberg HG. Novakovic B, et al. Among authors: zwaag j. Cell. 2016 Nov 17;167(5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. Cell. 2016. PMID: 27863248 Free PMC article.
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG. Domínguez-Andrés J, et al. Among authors: zwaag j. Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4. Cell Metab. 2019. PMID: 30293776 Free article.
Remote ischaemic preconditioning does not modulate the systemic inflammatory response or renal tubular stress biomarkers after endotoxaemia in healthy human volunteers: a single-centre, mechanistic, randomised controlled trial.
Zwaag J, Beunders R, Warlé MC, Kellum JA, Riksen NP, Pickkers P, Kox M. Zwaag J, et al. Br J Anaesth. 2019 Aug;123(2):177-185. doi: 10.1016/j.bja.2019.03.037. Epub 2019 May 10. Br J Anaesth. 2019. PMID: 31084985 Free PMC article. Clinical Trial.
Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects.
de Graaf DM, Jaeger M, van den Munckhof ICL, Ter Horst R, Schraa K, Zwaag J, Kox M, Fujita M, Yamauchi T, Mercurio L, Madonna S, Rutten JHW, de Graaf J, Riksen NP, van de Veerdonk FL, Netea MG, Joosten LAB, Dinarello CA. de Graaf DM, et al. Among authors: zwaag j. Eur J Immunol. 2021 Mar;51(3):662-671. doi: 10.1002/eji.201948390. Epub 2020 Nov 19. Eur J Immunol. 2021. PMID: 33125159 Free PMC article.
Lysine methyltransferase G9a is an important modulator of trained immunity.
Mourits VP, van Puffelen JH, Novakovic B, Bruno M, Ferreira AV, Arts RJ, Groh L, Crișan TO, Zwaag J, Jentho E, Kox M, Pickkers P, van de Veerdonk FL, Weis S, Oosterwijk E, Vermeulen SH, Netea MG, Joosten LA. Mourits VP, et al. Among authors: zwaag j. Clin Transl Immunology. 2021 Feb 18;10(2):e1253. doi: 10.1002/cti2.1253. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33708384 Free PMC article.
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