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Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.
Neumann-Haefelin C, Timm J, Schmidt J, Kersting N, Fitzmaurice K, Oniangue-Ndza C, Kemper MN, Humphreys I, McKiernan S, Kelleher D, Lohmann V, Bowness P, Huzly D, Rosen HR, Kim AY, Lauer GM, Allen TM, Barnes E, Roggendorf M, Blum HE, Thimme R. Neumann-Haefelin C, et al. Among authors: timm j. Hepatology. 2010 Jan;51(1):54-62. doi: 10.1002/hep.23275. Hepatology. 2010. PMID: 20034048 Free PMC article.
CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.
Khairnar V, Duhan V, Patil AM, Zhou F, Bhat H, Thoens C, Sharma P, Adomati T, Friendrich SK, Bezgovsek J, Dreesen JD, Wennemuth G, Westendorf AM, Zelinskyy G, Dittmer U, Hardt C, Timm J, Göthert JR, Lang PA, Singer BB, Lang KS. Khairnar V, et al. Among authors: timm j. Nat Commun. 2018 Jul 2;9(1):2561. doi: 10.1038/s41467-018-04832-2. Nat Commun. 2018. PMID: 29967450 Free PMC article.
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Huang A, Shinde PV, Huang J, Senff T, Xu HC, Margotta C, Häussinger D, Willnow TE, Zhang J, Pandyra AA, Timm J, Weggen S, Lang KS, Lang PA. Huang A, et al. Among authors: timm j. JCI Insight. 2019 Sep 5;4(17):e129856. doi: 10.1172/jci.insight.129856. JCI Insight. 2019. PMID: 31484831 Free PMC article.
362 results