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RNA interference-mediated silencing of Kv7.2 in rat dorsal root ganglion neurons abolishes the anti-nociceptive effect of a selective channel opener.
Valdor M, Wagner A, Fischer H, Röhrs V, Schröder W, Bahrenberg G, Welbers A, Fechner H, Kurreck J, Tzschentke TM, Christoph T. Valdor M, et al. Among authors: bahrenberg g. J Pharmacol Toxicol Methods. 2020 May-Jun;103:106693. doi: 10.1016/j.vascn.2020.106693. Epub 2020 Apr 8. J Pharmacol Toxicol Methods. 2020. PMID: 32276047
RNA interference-based functional knockdown of the voltage-gated potassium channel Kv7.2 in dorsal root ganglion neurons after in vitro and in vivo gene transfer by adeno-associated virus vectors.
Valdor M, Wagner A, Röhrs V, Berg J, Fechner H, Schröder W, Tzschentke TM, Bahrenberg G, Christoph T, Kurreck J. Valdor M, et al. Among authors: bahrenberg g. Mol Pain. 2018 Jan-Dec;14:1744806917749669. doi: 10.1177/1744806917749669. Epub 2017 Dec 6. Mol Pain. 2018. PMID: 29212407 Free PMC article.
A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration.
Bloms-Funke P, Schumacher M, Liu S, Su D, Li J, Liere P, Rupprecht R, Nothdurfter C, Bahrenberg G, Christoph T, Habermann C, Kneip C, Schröder W, Tzschentke TM, Saunders D. Bloms-Funke P, et al. Among authors: bahrenberg g. Eur J Pharmacol. 2022 May 15;923:174935. doi: 10.1016/j.ejphar.2022.174935. Epub 2022 Apr 2. Eur J Pharmacol. 2022. PMID: 35378102
Discovery of indane propanamides as potent and selective TRPV1 antagonists.
Ahn S, Kim YS, Kim MS, Ann J, Ha H, Yoo YD, Kim YH, Blumberg PM, Frank-Foltyn R, Bahrenberg G, Stockhausen H, Christoph T, Lee J. Ahn S, et al. Among authors: bahrenberg g. Bioorg Med Chem Lett. 2020 Feb 1;30(3):126838. doi: 10.1016/j.bmcl.2019.126838. Epub 2019 Dec 3. Bioorg Med Chem Lett. 2020. PMID: 31864799
43 results