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The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML.
Lin H, Rothe K, Chen M, Wu A, Babaian A, Yen R, Zeng J, Ruschmann J, Petriv OI, O'Neill K, Maetzig T, Knapp DJHF, Nakamichi N, Brinkman R, Birol I, Forrest DL, Hansen C, Humphries RK, Eaves CJ, Jiang X. Lin H, et al. Among authors: hansen c. Blood. 2020 Jul 30;136(5):596-609. doi: 10.1182/blood.2019003636. Blood. 2020. PMID: 32270193 Free PMC article.
Distinct signaling programs control human hematopoietic stem cell survival and proliferation.
Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, Eaves CJ. Knapp DJ, et al. Among authors: hansen c. Blood. 2017 Jan 19;129(3):307-318. doi: 10.1182/blood-2016-09-740654. Epub 2016 Nov 8. Blood. 2017. PMID: 27827829 Free PMC article.
MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz K, Ruschmann J, Lai C, Ngom M, Maetzig T, Martins V, Scheffold A, Schneider E, Pochert N, Miller C, Palmqvist L, Staffas A, Mulaw M, Bohl SR, Buske C, Heuser M, Kraus J, O'Neill K, Hansen CL, Petriv OI, Kestler H, Döhner H, Bullinger L, Döhner K, Humphries RK, Rouhi A, Kuchenbauer F. Krowiorz K, et al. Among authors: hansen cl. Blood Cancer J. 2016 Dec 9;6(12):e508. doi: 10.1038/bcj.2016.110. Blood Cancer J. 2016. PMID: 27935579 Free PMC article. No abstract available.
Ontogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factor.
Sekulovic S, Gasparetto M, Lecault V, Hoesli CA, Kent DG, Rosten P, Wan A, Brookes C, Hansen CL, Piret JM, Smith C, Eaves CJ, Humphries RK. Sekulovic S, et al. Among authors: hansen cl. Blood. 2011 Oct 20;118(16):4366-76. doi: 10.1182/blood-2011-04-350066. Epub 2011 Aug 24. Blood. 2011. PMID: 21865344 Free PMC article.
MicroRNA-146a disrupts hematopoietic differentiation and survival.
Starczynowski DT, Kuchenbauer F, Wegrzyn J, Rouhi A, Petriv O, Hansen CL, Humphries RK, Karsan A. Starczynowski DT, et al. Exp Hematol. 2011 Feb;39(2):167-178.e4. doi: 10.1016/j.exphem.2010.09.011. Epub 2010 Oct 7. Exp Hematol. 2011. PMID: 20933052 Free article.
Highly multiplexed single-cell quantitative PCR.
VanInsberghe M, Zahn H, White AK, Petriv OI, Hansen CL. VanInsberghe M, et al. PLoS One. 2018 Jan 29;13(1):e0191601. doi: 10.1371/journal.pone.0191601. eCollection 2018. PLoS One. 2018. PMID: 29377915 Free PMC article.
2,938 results