Newstead S - Search Results

1

Generation of synthetic nanobodies against delicate proteins.

Zimmermann I, Egloff P, Hutter CAJ, Kuhn BT, Bräuer P, Newstead S, Dawson RJP, Geertsma ER, Seeger MA. Zimmermann I, et al. Among authors: newstead s. Nat Protoc. 2020 May;15(5):1707-1741. doi: 10.1038/s41596-020-0304-x. Epub 2020 Apr 8. Nat Protoc. 2020. PMID: 32269381

2

Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor.

Bräuer P, Parker JL, Gerondopoulos A, Zimmermann I, Seeger MA, Barr FA, Newstead S. Bräuer P, et al. Among authors: newstead s. Science. 2019 Mar 8;363(6431):1103-1107. doi: 10.1126/science.aaw2859. Science. 2019. PMID: 30846601

3

A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrieval.

Gerondopoulos A, Bräuer P, Sobajima T, Wu Z, Parker JL, Biggin PC, Barr FA, Newstead S. Gerondopoulos A, et al. Among authors: newstead s. Elife. 2021 Jun 17;10:e68380. doi: 10.7554/eLife.68380. Elife. 2021. PMID: 34137369 Free PMC article.

4

Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410.

Remm S, De Vecchis D, Schöppe J, Hutter CAJ, Gonda I, Hohl M, Newstead S, Schäfer LV, Seeger MA. Remm S, et al. Among authors: newstead s. Nat Commun. 2023 Oct 13;14(1):6449. doi: 10.1038/s41467-023-42073-0. Nat Commun. 2023. PMID: 37833269 Free PMC article.

5

Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.

Rödström KEJ, Cloake A, Sörmann J, Baronina A, Smith KHM, Pike ACW, Ang J, Proks P, Schewe M, Holland-Kaye I, Bushell SR, Elliott J, Pardon E, Baukrowitz T, Owens RJ, Newstead S, Steyaert J, Carpenter EP, Tucker SJ. Rödström KEJ, et al. Among authors: newstead s. Nat Commun. 2024 May 16;15(1):4173. doi: 10.1038/s41467-024-48536-2. Nat Commun. 2024. PMID: 38755204 Free PMC article.

6

Structural basis of nucleotide sugar transport across the Golgi membrane.

Parker JL, Newstead S. Parker JL, et al. Among authors: newstead s. Nature. 2017 Nov 23;551(7681):521-524. doi: 10.1038/nature24464. Epub 2017 Nov 15. Nature. 2017. PMID: 29143814 Free PMC article.

7

Phasing statistics for alpha helical membrane protein structures.

Parker JL, Newstead S. Parker JL, et al. Among authors: newstead s. Protein Sci. 2013 Nov;22(11):1664-8. doi: 10.1002/pro.2341. Epub 2013 Sep 17. Protein Sci. 2013. PMID: 23963889 Free PMC article.

8

Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1.

Parker JL, Newstead S. Parker JL, et al. Among authors: newstead s. Nature. 2014 Mar 6;507(7490):68-72. doi: 10.1038/nature13116. Epub 2014 Feb 26. Nature. 2014. PMID: 24572366 Free PMC article.

9

GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae.

Drew D, Newstead S, Sonoda Y, Kim H, von Heijne G, Iwata S. Drew D, et al. Among authors: newstead s. Nat Protoc. 2008;3(5):784-98. doi: 10.1038/nprot.2008.44. Nat Protoc. 2008. PMID: 18451787 Free PMC article.

10

Crystal structures of a double-barrelled fluoride ion channel.

Stockbridge RB, Kolmakova-Partensky L, Shane T, Koide A, Koide S, Miller C, Newstead S. Stockbridge RB, et al. Among authors: newstead s. Nature. 2015 Sep 24;525(7570):548-51. doi: 10.1038/nature14981. Epub 2015 Sep 7. Nature. 2015. PMID: 26344196 Free PMC article.

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