Cai B - Search Results

1

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.

Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Among authors: cai b. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.

2

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation.

Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. Cai B, et al. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6526-31. doi: 10.1073/pnas.1524292113. Epub 2016 May 19. Proc Natl Acad Sci U S A. 2016. PMID: 27199481 Free PMC article.

3

Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.

Wang X, Zheng Z, Caviglia JM, Corey KE, Herfel TM, Cai B, Masia R, Chung RT, Lefkowitch JH, Schwabe RF, Tabas I. Wang X, et al. Among authors: cai b. Cell Metab. 2016 Dec 13;24(6):848-862. doi: 10.1016/j.cmet.2016.09.016. Epub 2016 Oct 27. Cell Metab. 2016. PMID: 28068223 Free PMC article.

4

Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages.

Wang Y, Subramanian M, Yurdagul A Jr, Barbosa-Lorenzi VC, Cai B, de Juan-Sanz J, Ryan TA, Nomura M, Maxfield FR, Tabas I. Wang Y, et al. Among authors: cai b. Cell. 2017 Oct 5;171(2):331-345.e22. doi: 10.1016/j.cell.2017.08.041. Epub 2017 Sep 21. Cell. 2017. PMID: 28942921 Free PMC article.

5

CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis.

Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I. Doran AC, et al. Among authors: cai b. J Clin Invest. 2017 Nov 1;127(11):4075-4089. doi: 10.1172/JCI94735. Epub 2017 Oct 3. J Clin Invest. 2017. PMID: 28972541 Free PMC article.

6

Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis.

Yurdagul A Jr, Doran AC, Cai B, Fredman G, Tabas IA. Yurdagul A Jr, et al. Among authors: cai b. Front Cardiovasc Med. 2018 Jan 8;4:86. doi: 10.3389/fcvm.2017.00086. eCollection 2017. Front Cardiovasc Med. 2018. PMID: 29379788 Free PMC article. Review.

7

The role of non-resolving inflammation in atherosclerosis.

Kasikara C, Doran AC, Cai B, Tabas I. Kasikara C, et al. Among authors: cai b. J Clin Invest. 2018 Jul 2;128(7):2713-2723. doi: 10.1172/JCI97950. Epub 2018 Jul 2. J Clin Invest. 2018. PMID: 30108191 Free PMC article. Review.

8

MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity.

Cai B, Kasikara C, Doran AC, Ramakrishnan R, Birge RB, Tabas I. Cai B, et al. Sci Signal. 2018 Sep 25;11(549):eaar3721. doi: 10.1126/scisignal.aar3721. Sci Signal. 2018. PMID: 30254055 Free PMC article.

9

An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1.

Zheng Z, Nayak L, Wang W, Yurdagul A Jr, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I. Zheng Z, et al. Among authors: cai b. Blood. 2019 Feb 14;133(7):743-753. doi: 10.1182/blood-2018-07-864843. Epub 2018 Dec 1. Blood. 2019. PMID: 30504459 Free PMC article.

10

A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice.

Wang X, Sommerfeld MR, Jahn-Hofmann K, Cai B, Filliol A, Remotti HE, Schwabe RF, Kannt A, Tabas I. Wang X, et al. Among authors: cai b. Hepatol Commun. 2019 Jul 23;3(9):1221-1234. doi: 10.1002/hep4.1405. eCollection 2019 Sep. Hepatol Commun. 2019. PMID: 31497743 Free PMC article.

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