Kauppila J - Search Results

1

A salvage pathway maintains highly functional respiratory complex I.

Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, Höhne MN, Hofsetz E, Becker C, Kaspar S, Giese H, Zwicker K, Guerrero-Castillo S, Baumann L, Kauppila J, Rumyantseva A, Müller S, Frese CK, Brandt U, Riemer J, Wittig I, Trifunovic A. Szczepanowska K, et al. Among authors: kauppila j. Nat Commun. 2020 Apr 2;11(1):1643. doi: 10.1038/s41467-020-15467-7. Nat Commun. 2020. PMID: 32242014 Free PMC article.

2

MitoTALEN reduces mutant mtDNA load and restores tRNA^Ala levels in a mouse model of heteroplasmic mtDNA mutation.

Bacman SR, Kauppila JHK, Pereira CV, Nissanka N, Miranda M, Pinto M, Williams SL, Larsson NG, Stewart JB, Moraes CT. Bacman SR, et al. Nat Med. 2018 Nov;24(11):1696-1700. doi: 10.1038/s41591-018-0166-8. Epub 2018 Sep 24. Nat Med. 2018. PMID: 30250143 Free PMC article.

3

Author Correction: MitoTALEN reduces mutant mtDNA load and restores tRNA^Ala levels in a mouse model of heteroplasmic mtDNA mutation.

Bacman SR, Kauppila JHK, Pereira CV, Nissanka N, Miranda M, Pinto M, Williams SL, Larsson NG, Stewart JB, Moraes CT. Bacman SR, et al. Nat Med. 2018 Dec;24(12):1940. doi: 10.1038/s41591-018-0234-0. Nat Med. 2018. PMID: 30291358

4

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.

Nicholls TJ, Spåhr H, Jiang S, Siira SJ, Koolmeister C, Sharma S, Kauppila JHK, Jiang M, Kaever V, Rackham O, Chabes A, Falkenberg M, Filipovska A, Larsson NG, Gustafsson CM. Nicholls TJ, et al. Among authors: kauppila jhk. Mol Cell. 2019 Dec 5;76(5):784-796.e6. doi: 10.1016/j.molcel.2019.09.010. Epub 2019 Oct 3. Mol Cell. 2019. PMID: 31588022 Free PMC article.

5

Mitochondrial DNA: Radically free of free-radical driven mutations.

Kauppila JH, Stewart JB. Kauppila JH, et al. Biochim Biophys Acta. 2015 Nov;1847(11):1354-61. doi: 10.1016/j.bbabio.2015.06.001. Epub 2015 Jun 4. Biochim Biophys Acta. 2015. PMID: 26050972 Free article. Review.

6

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.

Kauppila JHK, Baines HL, Bratic A, Simard ML, Freyer C, Mourier A, Stamp C, Filograna R, Larsson NG, Greaves LC, Stewart JB. Kauppila JHK, et al. Cell Rep. 2016 Sep 13;16(11):2980-2990. doi: 10.1016/j.celrep.2016.08.037. Cell Rep. 2016. PMID: 27626666 Free PMC article.

7

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.

Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG. Kauppila JHK, et al. Nucleic Acids Res. 2018 Jul 27;46(13):6642-6669. doi: 10.1093/nar/gky456. Nucleic Acids Res. 2018. PMID: 29860357 Free PMC article.

8

Mitochondrial fusion is required for regulation of mitochondrial DNA replication.

Silva Ramos E, Motori E, Brüser C, Kühl I, Yeroslaviz A, Ruzzenente B, Kauppila JHK, Busch JD, Hultenby K, Habermann BH, Jakobs S, Larsson NG, Mourier A. Silva Ramos E, et al. PLoS Genet. 2019 Jun 6;15(6):e1008085. doi: 10.1371/journal.pgen.1008085. eCollection 2019 Jun. PLoS Genet. 2019. PMID: 31170154 Free PMC article.

9

Mammalian Mitochondria and Aging: An Update.

Kauppila TES, Kauppila JHK, Larsson NG. Kauppila TES, et al. Cell Metab. 2017 Jan 10;25(1):57-71. doi: 10.1016/j.cmet.2016.09.017. Epub 2016 Oct 27. Cell Metab. 2017. PMID: 28094012 Free article. Review.

10

Perceived competency requirements for emergency medical services field supervisors in managing chemical and explosive incidents - qualitative interview study.

Kauppila J, Iirola T, Nordquist H. Kauppila J, et al. BMC Emerg Med. 2024 Dec 23;24(1):239. doi: 10.1186/s12873-024-01157-w. BMC Emerg Med. 2024. PMID: 39716075 Free PMC article.

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