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An intestinal organoid-based platform that recreates susceptibility to T-cell-mediated tissue injury.
Matsuzawa-Ishimoto Y, Hine A, Shono Y, Rudensky E, Lazrak A, Yeung F, Neil JA, Yao X, Chen YH, Heaney T, Schuster SL, Zwack EE, Axelrad JE, Hudesman D, Tsai JJ, Nichols K, Dewan MZ, Cammer M, Beal A, Hoffman S, Geddes B, Bertin J, Liu C, Torres VJ, Loke P, van den Brink MRM, Cadwell K. Matsuzawa-Ishimoto Y, et al. Among authors: hudesman d. Blood. 2020 Jun 25;135(26):2388-2401. doi: 10.1182/blood.2019004116. Blood. 2020. PMID: 32232483 Free PMC article.
Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells.
Tang MS, Bowcutt R, Leung JM, Wolff MJ, Gundra UM, Hudesman D, Malter LB, Poles MA, Chen LA, Pei Z, Neto AG, Abidi WM, Ullman T, Mayer L, Bonneau RA, Cho I, Loke P. Tang MS, et al. Among authors: hudesman d. Inflamm Bowel Dis. 2017 Sep;23(9):1544-1554. doi: 10.1097/MIB.0000000000001208. Inflamm Bowel Dis. 2017. PMID: 28806280 Free PMC article.
IFN-I and IL-22 mediate protective effects of intestinal viral infection.
Neil JA, Matsuzawa-Ishimoto Y, Kernbauer-Hölzl E, Schuster SL, Sota S, Venzon M, Dallari S, Galvao Neto A, Hine A, Hudesman D, Loke P, Nice TJ, Cadwell K. Neil JA, et al. Among authors: hudesman d. Nat Microbiol. 2019 Oct;4(10):1737-1749. doi: 10.1038/s41564-019-0470-1. Epub 2019 Jun 10. Nat Microbiol. 2019. PMID: 31182797 Free PMC article.
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Lee JY, Hall JA, Kroehling L, Wu L, Najar T, Nguyen HH, Lin WY, Yeung ST, Silva HM, Li D, Hine A, Loke P, Hudesman D, Martin JC, Kenigsberg E, Merad M, Khanna KM, Littman DR. Lee JY, et al. Among authors: hudesman d. Cell. 2020 Jan 9;180(1):79-91.e16. doi: 10.1016/j.cell.2019.11.026. Epub 2019 Dec 19. Cell. 2020. PMID: 31866067 Free PMC article.
86 results