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Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. Abdelsamed HA, et al. Among authors: youngblood b. Nat Immunol. 2020 May;21(5):578-587. doi: 10.1038/s41590-020-0633-5. Epub 2020 Mar 30. Nat Immunol. 2020. PMID: 32231298 Free PMC article.
Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells.
Youngblood B, Noto A, Porichis F, Akondy RS, Ndhlovu ZM, Austin JW, Bordi R, Procopio FA, Miura T, Allen TM, Sidney J, Sette A, Walker BD, Ahmed R, Boss JM, Sékaly RP, Kaufmann DE. Youngblood B, et al. J Immunol. 2013 Jul 15;191(2):540-4. doi: 10.4049/jimmunol.1203161. Epub 2013 Jun 14. J Immunol. 2013. PMID: 23772031 Free PMC article.
Cell-Intrinsic Barriers of T Cell-Based Immunotherapy.
Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA. Ghoneim HE, et al. Trends Mol Med. 2016 Dec;22(12):1000-1011. doi: 10.1016/j.molmed.2016.10.002. Epub 2016 Nov 4. Trends Mol Med. 2016. PMID: 27825667 Free PMC article. Review.
De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.
Ghoneim HE, Fan Y, Moustaki A, Abdelsamed HA, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas PG, Youngblood B. Ghoneim HE, et al. Among authors: youngblood b. Cell. 2017 Jun 29;170(1):142-157.e19. doi: 10.1016/j.cell.2017.06.007. Epub 2017 Jun 22. Cell. 2017. PMID: 28648661 Free PMC article.
In vitro Homeostatic Proliferation of Human CD8 T Cells.
Abdelsamed HA, Zebley CC, Youngblood B. Abdelsamed HA, et al. Among authors: youngblood b. Bio Protoc. 2017 Nov 20;7(22):e2619. doi: 10.21769/BioProtoc.2619. Bio Protoc. 2017. PMID: 29226183 Free PMC article.
156 results